| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 14 |
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| Ligand | BDBM50118239 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_635657 (CHEMBL1119549) |
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| EC50 | 160±n/a nM |
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| Citation |  Maruoka, H; Barrett, MO; Ko, H; Tosh, DK; Melman, A; Burianek, LE; Balasubramanian, R; Berk, B; Costanzi, S; Harden, TK; Jacobson, KA Pyrimidine ribonucleotides with enhanced selectivity as P2Y(6) receptor agonists: novel 4-alkyloxyimino, (S)-methanocarba, and 5'-triphosphate gamma-ester modifications. J Med Chem53:4488-501 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 14 |
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| Name: | P2Y purinoceptor 14 |
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| Synonyms: | GPR105 | Insulin Receptor-Related Protein (INSRR) | KIAA0001 | P2RY14 | P2Y14_HUMAN | Purinergic receptor P2Y14 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38991.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502487 |
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| Residue: | 338 |
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| Sequence: | MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYL
KNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRY
YKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELG
RKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVF
VFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQ
PFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
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| BDBM50118239 |
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| n/a |
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| Name | BDBM50118239 |
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| Synonyms: | CHEMBL130266 | UDP | Uridine diphosphate | uridine 5'-(trihydrogen diphosphate) |
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| Type | Small organic molecule |
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| Emp. Form. | C9H14N2O12P2 |
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| Mol. Mass. | 404.1612 |
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| SMILES | O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r| |
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| Structure | 
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