| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 2J2 |
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| Ligand | BDBM50319984 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_635054 (CHEMBL1119168) |
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| IC50 | 2000±n/a nM |
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| Citation |  Kowalski, JA; Swinamer, AD; Muegge, I; Eldrup, AB; Kukulka, A; Cywin, CL; De Lombaert, S Rapid synthesis of an array of trisubstituted urea-based soluble epoxide hydrolase inhibitors facilitated by a novel solid-phase method. Bioorg Med Chem Lett20:3703-7 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 2J2 |
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| Name: | Cytochrome P450 2J2 |
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| Synonyms: | CP2J2_HUMAN | CYP2J2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 57623.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51589 |
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| Residue: | 502 |
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| Sequence: | MLAAMGSLAAALWAVVHPRTLLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVD
FEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHI
FKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDP
HFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFL
PGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEEN
LICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMP
YTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDT
FNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLS
LKFRMGITISPVSHRLCAVPQV
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| BDBM50319984 |
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| n/a |
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| Name | BDBM50319984 |
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| Synonyms: | 4-(pyrimidin-2-yloxy)-N-(2-(trifluoromethoxy)benzyl)piperidine-1-carboxamide | CHEMBL1082684 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19F3N4O3 |
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| Mol. Mass. | 396.3637 |
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| SMILES | FC(F)(F)Oc1ccccc1CNC(=O)N1CCC(CC1)Oc1ncccn1 |
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| Structure | 
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