| Reaction Details |
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 | Report a problem with these data |
| Target | ATP-dependent 6-phosphofructokinase |
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| Ligand | BDBM50320385 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_634094 (CHEMBL1118878) |
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| Ki | 10000±n/a nM |
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| Citation |  Ngantchou, I; Nyasse, B; Denier, C; Blonski, C; Hannaert, V; Schneider, B Antitrypanosomal alkaloids from Polyalthia suaveolens (Annonaceae): their effects on three selected glycolytic enzymes of Trypanosoma brucei. Bioorg Med Chem Lett20:3495-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| ATP-dependent 6-phosphofructokinase |
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| Name: | ATP-dependent 6-phosphofructokinase |
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| Synonyms: | 6-phospho-1-fructokinase | PFKA_TRYBB | pfk |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53537.94 |
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| Organism: | Trypanosoma brucei |
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| Description: | ChEMBL_1288121 |
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| Residue: | 487 |
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| Sequence: | MAVESRSRVTSKLVKAHRAMLNSVTQEDLKVDRLPGADYPNPSKKYSSRTEFRDKTDYIM
YNPRPRDEPSSENPVSVSPLLCELAAARSRIHFNPTETTIGIVTCGGICPGLNDVIRSIT
LTGINVYNVKRVIGFRFGYWGLSKKGSQTAIELHRGRVTNIHHYGGTILGSSRGPQDPKE
MVDTLERLGVNILFTVGGDGTQRGALVISQEAKRRGVDISVFGVPKTIDNDLSFSHRTFG
FQTAVEKAVQAIRAAYAEAVSANYGVGVVKLMGRDSGFIAAQAAVASAQANICLVPENPI
SEQEVMSLLERRFCHSRSCVIIVAEGFGQDWGRGSGGYDASGNKKLIDIGVILTEKVKAF
LKANKSRYPDSTVKYIDPSYMIRACPPSANDALFCATLATLAVHEAMAGATGCIIAMRHN
NYILVPIKVATSVRRVLDLRGQLWRQVREITVDLGSDVRLARKLEIRRELEAINRNRDRL
HEELAKL
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| BDBM50320385 |
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| n/a |
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| Name | BDBM50320385 |
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| Synonyms: | (4aR,6aR,12bS)-4,4,6a,12b-Tetramethyl-1,4a,5,6,6a,12,12a,12b-octahydro-2H,4H-6b-aza-benzo[5,6]pentaleno[2,1-b]naphthalen-3-one | CHEMBL1082691 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29NO |
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| Mol. Mass. | 335.4825 |
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| SMILES | C[C@@]12CC[C@H]3C(C)(C)C(=O)CC[C@]3(C)C1Cc1cc3ccccc3n21 |r| |
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| Structure | 
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