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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Dipeptidyl peptidase 9 | ||
| Ligand | BDBM50323181 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_643844 (CHEMBL1211743) | ||
| Ki | >30000±n/a nM | ||
| Citation |  Brigance, RP; Meng, W; Fura, A; Harrity, T; Wang, A; Zahler, R; Kirby, MS; Hamann, LG Synthesis and SAR of azolopyrimidines as potent and selective dipeptidyl peptidase-4 (DPP4) inhibitors for type 2 diabetes. Bioorg Med Chem Lett20:4395-8 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Dipeptidyl peptidase 9 | |||
| Name: | Dipeptidyl peptidase 9 | ||
| Synonyms: | DPP9 | DPP9_HUMAN | DPRP-2 | DPRP2 | Dipeptidyl peptidase 9 (DDP9) | Dipeptidyl peptidase 9 (DPP-9) | Dipeptidyl peptidase 9 (DPP9) | Dipeptidyl peptidase IV-related protein 2 | Dipeptidyl peptidase IX | Dipeptidyl peptidase IX (DDP-IX) | Dipeptidyl peptidase-like protein 9 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 98260.70 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q86TI2 | ||
| Residue: | 863 | ||
| Sequence: |
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| BDBM50323181 | |||
| n/a | |||
| Name | BDBM50323181 | ||
| Synonyms: | (7-(2,4-dichlorophenyl)-2,5-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)methanamine | CHEMBL1209681 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C14H13Cl2N5 | ||
| Mol. Mass. | 322.193 | ||
| SMILES | Cc1nc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)n2n1 |(-9.97,3.4,;-8.43,3.41,;-7.54,4.67,;-6.07,4.2,;-4.73,4.98,;-3.39,4.21,;-2.06,4.98,;-3.39,2.67,;-2.06,1.91,;-.73,2.68,;-4.73,1.91,;-4.73,.37,;-6.04,-.4,;-6.04,-1.95,;-4.71,-2.72,;-4.71,-4.26,;-3.37,-1.95,;-3.4,-.4,;-2.06,.37,;-6.06,2.66,;-7.52,2.17,)| | ||
| Structure | 
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