| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50325036 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_651609 (CHEMBL1227992) |
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| IC50 | 290±n/a nM |
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| Citation |  Lee, GN; Kim, KR; Ahn, SH; Bae, MA; Kang, NS Discovery of cannabinoid-1 receptor antagonists by virtual screening. Bioorg Med Chem Lett20:5130-2 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52868.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21554 |
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| Residue: | 472 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50325036 |
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| n/a |
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| Name | BDBM50325036 |
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| Synonyms: | CHEMBL1223234 | [6,6-Dimethyl-3-(2-methyl-allyl)-4-oxo-3,5,6,8-tetrahydro-4H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl]-acetic acid methyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22N2O4S2 |
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| Mol. Mass. | 394.508 |
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| SMILES | COC(=O)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CC(C)=C |
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| Structure | 
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