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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tumor necrosis factor receptor superfamily member 5 | ||
| Ligand | BDBM50325994 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_660437 (CHEMBL1250027) | ||
| IC50 | 78±n/a nM | ||
| Citation |  Fournel, S; Wieckowski, S; Sun, W; Trouche, N; Dumortier, H; Bianco, A; Chaloin, O; Habib, M; Peter, JC; Schneider, P; Vray, B; Toes, RE; Offringa, R; Melief, CJ; Hoebeke, J; Guichard, G C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L. Nat Chem Biol1:377-82 (2005) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tumor necrosis factor receptor superfamily member 5 | |||
| Name: | Tumor necrosis factor receptor superfamily member 5 | ||
| Synonyms: | B-cell surface antigen CD40 | Bp50 | CD40 | CD40L receptor | CD_antigen=CD40 | CDw40 | TNFRSF5 | TNR5_HUMAN | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 30614.16 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_660437 | ||
| Residue: | 277 | ||
| Sequence: |
| ||
| BDBM50325994 | |||
| n/a | |||
| Name | BDBM50325994 | ||
| Synonyms: | (2S,2'S,2''S)-N,N',N''-((4S,4'S,4''S,7S,7'S,7''S)-20,20',20''-((2S,5R,8S,11R,14S,17R)-5,11,17-trimethyl-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexaazacyclooctadecane-2,8,14-triyl)tris(4,7-bis(4-hydroxybenzyl)-2,5,8,15-tetraoxo-3'',6'',9'',16''-tetraazaicosane-20,1-diyl))tris(2,6-diaminohexanamide) | CHEMBL1241017 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C123H183N27O27 | ||
| Mol. Mass. | 2471.9338 | ||
| SMILES | C[C@H]1NC(=O)[C@H](CCCCNC(=O)CCCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CNC(=O)[C@@H](N)CCCCN)NC(=O)[C@@H](C)NC(=O)[C@H](CCCCNC(=O)CCCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CNC(=O)[C@@H](N)CCCCN)NC(=O)[C@@H](C)NC(=O)[C@H](CCCCNC(=O)CCCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CNC(=O)[C@@H](N)CCCCN)NC1=O |r| | ||
| Structure | 
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