Reaction Details | |||
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Target | Tumor necrosis factor receptor superfamily member 5 | ||
Ligand | BDBM50325996 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_660437 (CHEMBL1250027) | ||
IC50 | 9900±n/a nM | ||
Citation | Fournel, S; Wieckowski, S; Sun, W; Trouche, N; Dumortier, H; Bianco, A; Chaloin, O; Habib, M; Peter, JC; Schneider, P; Vray, B; Toes, RE; Offringa, R; Melief, CJ; Hoebeke, J; Guichard, G C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L. Nat Chem Biol1:377-82 (2005) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Tumor necrosis factor receptor superfamily member 5 | |||
Name: | Tumor necrosis factor receptor superfamily member 5 | ||
Synonyms: | B-cell surface antigen CD40 | Bp50 | CD40 | CD40L receptor | CD_antigen=CD40 | CDw40 | TNFRSF5 | TNR5_HUMAN | ||
Type: | PROTEIN | ||
Mol. Mass.: | 30614.16 | ||
Organism: | Homo sapiens (Human) | ||
Description: | ChEMBL_660437 | ||
Residue: | 277 | ||
Sequence: |
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BDBM50325996 | |||
n/a | |||
Name | BDBM50325996 | ||
Synonyms: | CHEMBL1241019 | N1-((5S,11S,14S,44S,47S,53S)-1,5,53,57-tetraamino-29-((15S,18S,24S)-24,28-diamino-15,18-bis(4-hydroxybenzyl)-7,14,17,20,23-pentaoxo-2-oxa-6,13,16,19,22-pentaazaoctacosyl)-11,14,44,47-tetrakis(4-hydroxybenzyl)-6,9,12,15,22,36,43,46,49,52-decaoxo-27,31-dioxa-7,10,13,16,23,35,42,45,48,51-decaazaheptapentacontan-29-yl)succinamide | ||
Type | Small organic molecule | ||
Emp. Form. | C113H169N23O26 | ||
Mol. Mass. | 2265.6895 | ||
SMILES | NCCCC[C@H](N)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCCCCC(=O)NCCCOCC(COCCCNC(=O)CCCCCNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@@H](N)CCCCN)(COCCCNC(=O)CCCCCNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@@H](N)CCCCN)NC(=O)CCC(N)=O |r| | ||
Structure |