| Reaction Details |
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 | Report a problem with these data |
| Target | Polyphenol oxidase 2 |
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| Ligand | BDBM50326456 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_658045 (CHEMBL1248957) |
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| Ki | 38000±n/a nM |
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| Citation |  Bao, K; Dai, Y; Zhu, ZB; Tu, FJ; Zhang, WG; Yao, XS Design and synthesis of biphenyl derivatives as mushroom tyrosinase inhibitors. Bioorg Med Chem18:6708-14 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Polyphenol oxidase 2 |
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| Name: | Polyphenol oxidase 2 |
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| Synonyms: | Monophenol monooxygenase | Monophenol oxidase | PPO2 | PPO2_AGABI | Tyrosinase |
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| Type: | Protein |
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| Mol. Mass.: | 63923.66 |
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| Organism: | Agaricus bisporus (Common mushroom) |
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| Description: | O42713 |
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| Residue: | 556 |
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| Sequence: | MSLIATVGPTGGVKNRLNIVDFVKNEKFFTLYVRSLELLQAKEQHDYSSFFQLAGIHGLP
FTEWAKERPSMNLYKAGYCTHGQVLFPTWHRTYLSVLEQILQGAAIEVAKKFTSNQTDWV
QAAQDLRQPYWDWGFELMPPDEVIKNEEVNITNYDGKKISVKNPILRYHFHPIDPSFKPY
GDFATWRTTVRNPDRNRREDIPGLIKKMRLEEGQIREKTYNMLKFNDAWERFSNHGISDD
QHANSLESVHDDIHVMVGYGKIEGHMDHPFFAAFDPIFWLHHTNVDRLLSLWKAINPDVW
VTSGRNRDGTMGIAPNAQINSETPLEPFYQSGDKVWTSASLADTARLGYSYPDFDKLVGG
TKELIRDAIDDLIDERYGSKPSSGARNTAFDLLADFKGITKEHKEDLKMYDWTIHVAFKK
FELKESFSLLFYFASDGGDYDQENCFVGSINAFRGTAPETCANCQDNENLIQEGFIHLNH
YLARDLESFEPQDVHKFLKEKGLSYKLYSRGDKPLTSLSVKIEGRPLHLPPGEHRPKYDH
TQARVVFDDVAVHVIN
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| BDBM50326456 |
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| n/a |
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| Name | BDBM50326456 |
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| Synonyms: | 4'-Hydroxy-3',5'-dimethoxybiphenyl-4-carboxylic acid | CHEMBL1241468 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14O5 |
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| Mol. Mass. | 274.2687 |
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| SMILES | COc1cc(cc(OC)c1O)-c1ccc(cc1)C(O)=O |
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| Structure | 
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