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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | MHC class II antigen | ||
| Ligand | BDBM50326697 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_661466 (CHEMBL1252964) | ||
| IC50 | 0.6±n/a nM | ||
| Citation |  Venkatraman, P; Nguyen, TT; Sainlos, M; Bilsel, O; Chitta, S; Imperiali, B; Stern, LJ Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells. Nat Chem Biol3:222-8 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| MHC class II antigen | |||
| Name: | MHC class II antigen | ||
| Synonyms: | DR-1 | DR1 | HLA class II histocompatibility antigen DRB1-1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | Human leukocyte antigen DR beta chain | MHC class I antigen DRB1*1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 29917.79 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_192854 | ||
| Residue: | 266 | ||
| Sequence: |
| ||
| BDBM50326697 | |||
| n/a | |||
| Name | BDBM50326697 | ||
| Synonyms: | (3S,6S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S)-18-(2-amino-2-oxoethyl)-1-((S)-1-((S)-2-amino-3-(5-(dimethylamino)-1,3-dioxoisoindolin-2-yl)propanoyl)pyrrolidin-2-yl)-15-(3-amino-3-oxopropyl)-3,12,27-tris(4-aminobutyl)-6-(4-hydroxybenzyl)-21,36-bis((R)-1-hydroxyethyl)-24,30-diisobutyl-9-isopropyl-33-methyl-1,4,7,10,13,16,19,22,25,28,31,34-dodecaoxo-2,5,8,11,14,17,20,23,26,29,32,35-dodecaazaheptatriacontan-37-oic acid | CHEMBL1253324 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C82H131N21O22 | ||
| Mol. Mass. | 1763.045 | ||
| SMILES | CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CN1C(=O)c2ccc(cc2C1=O)N(C)C)C(C)C)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(O)=O |r| | ||
| Structure | 
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