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TargetHLA class II histocompatibility antigen DRB1-1
LigandBDBM50326697
Substrate/Competitorn/a
Meas. Tech.ChEMBL_661466
IC50 0.6±n/a nM
Citation Venkatraman PNguyen TTSainlos MBilsel OChitta SImperiali BStern LJ Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells. Nat Chem Biol 3:222-8 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
HLA class II histocompatibility antigen DRB1-1
Name:Human leukocyte antigen DR beta chain
Synonyms:DR-1 | DR1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | MHC class I antigen DRB1*1
Type:PROTEIN
Mol. Mass.:29917.79
Organism:Homo sapiens (Human)
Description:ChEMBL_192854
Residue:266
Sequence:
MVCLKLPGGSCMTALTVTLMVLSSPLALAGDTRPRFLWQLKFECHFFNGTERVRLLERCI
YNQEESVRFDSDVGEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV
QRRVEPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL
FLGAGLFIYFRNQKGHSGLQPTGFLS
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  Blast E-value cutoff:
BDBM50326697
n/a
NameBDBM50326697
Synonyms:(3S,6S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S)-18-(2-amino-2-oxoethyl)-1-((S)-1-((S)-2-amino-3-(5-(dimethylamino)-1,3-dioxoisoindolin-2-yl)propanoyl)pyrrolidin-2-yl)-15-(3-amino-3-oxopropyl)-3,12,27-tris(4-aminobutyl)-6-(4-hydroxybenzyl)-21,36-bis((R)-1-hydroxyethyl)-24,30-diisobutyl-9-isopropyl-33-methyl-1,4,7,10,13,16,19,22,25,28,31,34-dodecaoxo-2,5,8,11,14,17,20,23,26,29,32,35-dodecaazaheptatriacontan-37-oic acid | CHEMBL1253324
TypeSmall organic molecule
Emp. Form.C82H131N21O22
Mol. Mass.1763.045
SMILESCC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CN1C(=O)c2ccc(cc2C1=O)N(C)C)C(C)C)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(O)=O |r|
Structure
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