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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | MHC class II antigen | ||
| Ligand | BDBM50326703 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_661478 (CHEMBL1253009) | ||
| IC50 | 28±n/a nM | ||
| Citation |  Venkatraman, P; Nguyen, TT; Sainlos, M; Bilsel, O; Chitta, S; Imperiali, B; Stern, LJ Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells. Nat Chem Biol3:222-8 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| MHC class II antigen | |||
| Name: | MHC class II antigen | ||
| Synonyms: | DR-1 | DR1 | HLA class II histocompatibility antigen DRB1-1 | HLA class II histocompatibility antigen, DRB1-1 beta chain | Human leukocyte antigen DR beta chain | MHC class I antigen DRB1*1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 29917.79 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_192854 | ||
| Residue: | 266 | ||
| Sequence: |
| ||
| BDBM50326703 | |||
| n/a | |||
| Name | BDBM50326703 | ||
| Synonyms: | (5S,8S,11S,14S,17S,20S,23S,26S,29S)-5-acetamido-1-(2-carboxy-4-(dimethylamino)phenyl)-8-(3-guanidinopropyl)-11-(hydroxymethyl)-17,20,23,26,31-pentamethyl-14-(2-(methylthio)ethyl)-2,6,9,12,15,18,21,24,27-nonaoxo-3,7,10,13,16,19,22,25,28-nonaazadotriacontane-29-carboxylic acid | CHEMBL1253327 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C48H78N14O15S | ||
| Mol. Mass. | 1123.283 | ||
| SMILES | [#6]-[#16]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#7]-[#6](=O)-[#6]-c1ccc(cc1-[#6](-[#8])=O)-[#7](-[#6])-[#6])-[#7]-[#6](-[#6])=O)-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](-[#8])=O |r| | ||
| Structure | 
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