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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Protein Mdm4 | ||
| Ligand | BDBM50327206 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_664225 (CHEMBL1261732) | ||
| Kd | 390±n/a nM | ||
| Citation |  Datta, S; Bucks, ME; Koley, D; Lim, PX; Savinov, SN Functional profiling of p53-binding sites in Hdm2 and Hdmx using a genetic selection system. Bioorg Med Chem18:6099-108 (2010) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Protein Mdm4 | |||
| Name: | Protein Mdm4 | ||
| Synonyms: | Double minute 4 protein | Double minute 4 protein (HDM4) | MDM2-MDMX | MDM4 | MDM4_HUMAN | MDMX | Mdm2-like p53-binding protein | Protein Mdm4 | Protein Mdmx | p53-Binding Protein HDMX | p53-binding protein | p53-binding protein Mdm4 | ||
| Type: | Oncoprotein | ||
| Mol. Mass.: | 54842.04 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | The HDMX(1-188) were expressed in Escherichia coli BL21 (DE3) as a GST fusion and purified on glutathione sepharose. | ||
| Residue: | 490 | ||
| Sequence: |
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| BDBM50327206 | |||
| n/a | |||
| Name | BDBM50327206 | ||
| Synonyms: | (2S,5S,8S,11S,14S,17S,20S,23S,26S,29S)-11-((1H-indol-3-yl)methyl)-29-amino-8-(4-aminobutyl)-23-benzyl-17-(carboxymethyl)-26-((R)-1-hydroxyethyl)-20-(hydroxymethyl)-2,5,14-triisobutyl-4,7,10,13,16,19,22,25,28-nonaoxo-3,6,9,12,15,18,21,24,27-nonaazadotriacontane-1,32-dioic acid | CHEMBL1256072 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C60H90N12O17 | ||
| Mol. Mass. | 1251.4268 | ||
| SMILES | CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(O)=O |r| | ||
| Structure | 
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