| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50329340 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_675428 (CHEMBL1273565) |
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| Ki | 40±n/a nM |
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| Citation |  McGuinness, BF; Cole, AG; Dong, G; Brescia, MR; Shao, Y; Henderson, I; Rokosz, LL; Stauffer, TM; Mannava, N; Kimble, EF; Hicks, C; White, N; Wines, PG; Quadros, E Discovery of 2-aminoimidazopyridine adenosine A(2A) receptor antagonists. Bioorg Med Chem Lett20:6845-9 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50329340 |
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| n/a |
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| Name | BDBM50329340 |
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| Synonyms: | CHEMBL1270414 | N-butyl-2-(3-cyanobenzamido)-3-(3-methoxypropyl)-3H-imidazo[4,5-b]pyridine-6-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26N6O3 |
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| Mol. Mass. | 434.4909 |
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| SMILES | CCCCNC(=O)c1cnc2n(CCCOC)c(NC(=O)c3cccc(c3)C#N)nc2c1 |
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| Structure | 
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