| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen phosphorylase, muscle form |
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| Ligand | BDBM50330796 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_685480 (CHEMBL1285511) |
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| Ki | 4600±n/a nM |
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| Citation |  Alexacou, KM; Tenchiu Deleanu, AC; Chrysina, ED; Charavgi, MD; Kostas, ID; Zographos, SE; Oikonomakos, NG; Leonidas, DD The binding ofß-d-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors. Bioorg Med Chem18:7911-22 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycogen phosphorylase, muscle form |
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| Name: | Glycogen phosphorylase, muscle form |
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| Synonyms: | Glycogen phosphorylase, muscle form | Muscle glycogen phosphorylase | Myophosphorylase | PYGM | PYGM_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 97097.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1449751 |
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| Residue: | 842 |
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| Sequence: | MSRPLSDQEKRKQISVRGLAGVENVTELKKNFNRHLHFTLVKDRNVATPRDYYFALAHTV
RDHLVGRWIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDM
EELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKISGGWQMEEA
DDWLRYGNPWEKARPEFTLPVHFYGHVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVN
TMRLWSAKAPNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFV
VAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRILVDLERM
DWDKAWDVTVRTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFP
GDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKF
QNKTNGITPRRWLVLCNPGLAEVIAERIGEDFISDLDQLRKLLSFVDDEAFIRDVAKVKQ
ENKLKFAAYLEREYKVHINPNSLFDIQVKRIHEYKRQLLNCLHVITLYNRIKREPNKFFV
PRTVMIGGKAAPGYHMAKMIIRLVTAIGDVVNHDPAVGDRLRVIFLENYRVSLAEKVIPA
ADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVEDVD
KLDQRGYNAQEYYDRIPELRQVIEQLSSGFFSPKQPDLFKDIVNMLMHHDRFKVFADYED
YIKCQEKVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRLPAPDE
AI
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| BDBM50330796 |
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| n/a |
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| Name | BDBM50330796 |
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| Synonyms: | 4-Fluoro-benzaldehyde4-(beta-D-glucopyranosyl)thiosemicarbazone | CHEMBL1277321 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H20FN3O4S |
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| Mol. Mass. | 357.4 |
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| SMILES | CC[C@H]1O[C@@H](NC(=S)NN=Cc2ccc(F)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r,w:9.8| |
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| Structure | 
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