Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50026752 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_687290 (CHEMBL1291966) |
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Ki | 920±n/a nM |
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Citation | Gu, X; Izenwasser, S; Wade, D; Housman, A; Gulasey, G; Rhoden, JB; Savoie, CD; Mobley, DL; Lomenzo, SA; Trudell, ML Synthesis and structure-activity studies of benzyl ester meperidine and normeperidine derivatives as selective serotonin transporter ligands. Bioorg Med Chem18:8356-64 (2010) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 44789.51 |
Organism: | Homo sapiens (Human) |
Description: | P35372 |
Residue: | 400 |
Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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BDBM50026752 |
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n/a |
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Name | BDBM50026752 |
Synonyms: | 1-Methyl-4-phenyl-piperidine-4-carboxylic acid ethyl ester | 1-Methyl-4-phenyl-piperidine-4-carboxylic acid ethyl ester(Meperidine) | 4-Ethoxycarbonyl-1-methyl-4-phenyl-piperidinium | CHEMBL607 | Demerol | MEPERIDINE | MEPERIDINE HYDROCHLORIDE | Mepergan | Pethidine | ethyl 1-methyl-4-phenylpiperidine-4-carboxylate |
Type | Small organic molecule |
Emp. Form. | C15H21NO2 |
Mol. Mass. | 247.3327 |
SMILES | CCOC(=O)C1(CCN(C)CC1)c1ccccc1 |
Structure |
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