| Reaction Details |
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 | Report a problem with these data |
| Target | Endochitinase A1 |
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| Ligand | BDBM10868 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_686888 (CHEMBL1291257) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Schüttelkopf, AW; Gros, L; Blair, DE; Frearson, JA; van Aalten, DM; Gilbert, IH Acetazolamide-based fungal chitinase inhibitors. Bioorg Med Chem18:8334-40 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Endochitinase A1 |
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| Name: | Endochitinase A1 |
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| Synonyms: | CHIA1_ASPFM | Chitinase (chiA1) | chi1 | chiA1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 83057.83 |
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| Organism: | Neosartorya fumigata (Aspergillus fumigatus) |
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| Description: | Q873Y0 |
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| Residue: | 825 |
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| Sequence: | MVSSKLSFVATAVAALAPLASAFDASSRSNLAIYWGQGPNQLRLSHFCQETSLDIINIGF
INYFPDMSPGHWPGSNFGNQCDGSVYVTNDGVVTKLLSGCHQIMEDIPICQAAGKKVLLS
IGGAYPPDQSILSEDSAVAFATFLWGAFGPVAEGWEGPRPFGDVVVDGFDFDIEHNGGFG
YATMVNTFRQYFNQVPERKFYLSAAPQCIIPDAQLSDAIFNAAFDFIWIQYYNTAACSAK
SFIDTSLGTFNFDAWVTVLKASASKDAKLYVGLPASETAANQGYYLTPDEVESLVSTYMD
RYPDTFGGIMLWEATASENNQIDGAPYADHMKDILLHCDPSPPVTSSSAVPSSTPVTTPS
PSSSAVPSSTPAVSETPSPSSSAVPSSTPVASSTPVVPGTSASSSPVSSSSAIAPSTPVV
PGTSTPSSTPVASSTPVVPGTSASSSPVSSSSAVASSTPVVPGTSVPSSTPAIPGGSSSS
SEAVASSTPLVTLTLTVSPTPAPSSSESSSTDLSSSTQTDVGTAPSQPAGPSTTATATTS
SSSSSTDESSTTVGSGNGNGSGSTTTTAATDSITAAPTATSSATATGATSEPVTITTIIV
TSYIDICPTGFTTVTTTYTTTYCPGTNTATATATVTNPPSGPGGAGSQTTAPTVPEGWTT
TVTVCTQCAAKPTTVTLTLPVTETGSTSTDAVPAPPAATGEGSNPTQPSGASPTGGNGSF
SEEPVPPPAVTQVSTSTEIVTLVRPTSSRPLILGTGTVHPSSTLAVKPSAKPSGQNSGSS
SHVPIPPSYTQEAVSPLSTGAASRVTGLGHGLVLTVLTLSAFFVL
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| BDBM10868 |
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| n/a |
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| Name | BDBM10868 |
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| Synonyms: | 1,3,4-Thiadiazole-2-sulfonamide, 6 | 1,3,4-thiadiazole-2-sulfonamide 15 | 5-Amino-1,3,4-thiadiazole-2-sulphonamide (1) | 5-amino-1,3,4-thiadiazole-2-sulfonamide | CHEMBL265674 | aromatic/heteroaromatic sulfonamide 13 |
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| Type | Small organic molecule |
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| Emp. Form. | C2H4N4O2S2 |
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| Mol. Mass. | 180.209 |
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| SMILES | Nc1nnc(s1)S(N)(=O)=O |
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| Structure | 
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