| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate receptor ionotropic, kainate 2 |
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| Ligand | BDBM50128264 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_690218 (CHEMBL1634348) |
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| Ki | >100000±n/a nM |
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| Citation |  Frydenvang, K; Pickering, DS; Greenwood, JR; Krogsgaard-Larsen, N; Brehm, L; Nielsen, B; Vogensen, SB; Hald, H; Kastrup, JS; Krogsgaard-Larsen, P Biostructural and Pharmacological Studies of Bicyclic Analogues of the 3-Isoxazolol Glutamate Receptor Agonist Ibotenic Acid J Med Chem53:8354-8361 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamate receptor ionotropic, kainate 2 |
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| Name: | Glutamate receptor ionotropic, kainate 2 |
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| Synonyms: | GRIK2_RAT | Glur6 | Glutamate receptor ionotropic kainate 2 | Grik2 | Ionotropic glutamate receptor kainate 2/5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 102478.61 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_936439 |
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| Residue: | 908 |
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| Sequence: | MKIISPVLSNLVFSRSIKVLLCLLWIGYSQGTTHVLRFGGIFEYVESGPMGAEELAFRFA
VNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQS
ICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDST
GLIRLQELIKAPSRYNLRLKIRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILK
QALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMER
LQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQCNRHKPWRFGTRFM
SLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGK
PANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEI
RLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISI
LYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSD
VVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLT
VERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKS
NEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITI
AILQLQEEGKLHMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVG
EFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLKHKPQAPVIVKTEEVINMHTFNDRR
LPGKETMA
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| BDBM50128264 |
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| n/a |
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| Name | BDBM50128264 |
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| Synonyms: | (R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionate | 2-Amino-3-(4-chloro-3-hydroxy-isoxazol-5-yl)-propionic acid | CHEMBL72366 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H7ClN2O4 |
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| Mol. Mass. | 206.584 |
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| SMILES | NC(Cc1o[nH]c(=O)c1Cl)C(O)=O |
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| Structure | 
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