| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin D2 receptor |
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| Ligand | BDBM50333492 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_699227 (CHEMBL1646949) |
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| Ki | >3400±n/a nM |
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| Citation |  Simard, D; Leblanc, Y; Berthelette, C; Zaghdane, MH; Molinaro, C; Wang, Z; Gallant, M; Lau, S; Thao, T; Hamel, M; Stocco, R; Sawyer, N; Sillaots, S; Gervais, F; Houle, R; Lévesque, JF Azaindoles as potent CRTH2 receptor antagonists. Bioorg Med Chem Lett21:841-5 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin D2 receptor |
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| Name: | Prostaglandin D2 receptor |
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| Synonyms: | PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40288.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13258 |
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| Residue: | 359 |
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| Sequence: | MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSV
FYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST
LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPG
TWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT
RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS
EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
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| BDBM50333492 |
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| n/a |
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| Name | BDBM50333492 |
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| Synonyms: | (R)-2-(7-(4-fluoro-N-methylphenylsulfonamido)-6,7,8,9-tetrahydropyrido[3,4-b]indolizin-10-yl)acetic acid | CHEMBL1641806 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20FN3O4S |
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| Mol. Mass. | 417.454 |
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| SMILES | CN([C@@H]1CCc2c(CC(O)=O)c3cnccc3n2C1)S(=O)(=O)c1ccc(F)cc1 |r| |
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| Structure | 
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