| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin D2 receptor |
|---|
| Ligand | BDBM50333491 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_699227 (CHEMBL1646949) |
|---|
| Ki | >4000±n/a nM |
|---|
| Citation |  Simard, D; Leblanc, Y; Berthelette, C; Zaghdane, MH; Molinaro, C; Wang, Z; Gallant, M; Lau, S; Thao, T; Hamel, M; Stocco, R; Sawyer, N; Sillaots, S; Gervais, F; Houle, R; Lévesque, JF Azaindoles as potent CRTH2 receptor antagonists. Bioorg Med Chem Lett21:841-5 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin D2 receptor |
|---|
| Name: | Prostaglandin D2 receptor |
|---|
| Synonyms: | PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40288.87 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q13258 |
|---|
| Residue: | 359 |
|---|
| Sequence: | MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSV
FYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST
LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPG
TWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT
RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS
EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
|
|
|
|---|
| BDBM50333491 |
|---|
| n/a |
|---|
| Name | BDBM50333491 |
|---|
| Synonyms: | (R)-2-(8-(1-(4-fluorophenyl)-N-methylcyclopentanecarboxamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid | CHEMBL1641817 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H28FN3O3 |
|---|
| Mol. Mass. | 449.5172 |
|---|
| SMILES | CN([C@@H]1CCc2c(CC(O)=O)c3cccnc3n2C1)C(=O)C1(CCCC1)c1ccc(F)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
