Reaction Details |
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Target | Thromboxane A2 receptor |
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Ligand | BDBM50333503 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_699228 (CHEMBL1646950) |
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Ki | >7200±n/a nM |
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Citation | Simard, D; Leblanc, Y; Berthelette, C; Zaghdane, MH; Molinaro, C; Wang, Z; Gallant, M; Lau, S; Thao, T; Hamel, M; Stocco, R; Sawyer, N; Sillaots, S; Gervais, F; Houle, R; Lévesque, JF Azaindoles as potent CRTH2 receptor antagonists. Bioorg Med Chem Lett21:841-5 (2011) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Thromboxane A2 receptor |
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Name: | Thromboxane A2 receptor |
Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
Type: | Enyzme |
Mol. Mass.: | 37445.28 |
Organism: | Homo sapiens (Human) |
Description: | P21731 |
Residue: | 343 |
Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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BDBM50333503 |
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n/a |
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Name | BDBM50333503 |
Synonyms: | (R)-2-(8-(4-(4-fluorophenyl)-N-methyltetrahydro-2H-pyran-4-carboxamido)-6,7,8,9-tetrahydropyrido[3,2-b]indolizin-5-yl)acetic acid | CHEMBL1641818 |
Type | Small organic molecule |
Emp. Form. | C26H28FN3O4 |
Mol. Mass. | 465.5166 |
SMILES | CN([C@@H]1CCc2c(CC(O)=O)c3cccnc3n2C1)C(=O)C1(CCOCC1)c1ccc(F)cc1 |r| |
Structure |
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