| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP4 subtype |
|---|
| Ligand | BDBM50333730 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_700672 (CHEMBL1645711) |
|---|
| Ki | 134±n/a nM |
|---|
| Citation |  Li, L; Mathieu, MC; Denis, D; Therien, AG; Wang, Z The identification of substituted benzothiophene derivatives as PGE(2) subtype 4 receptor antagonists: From acid to non-acid. Bioorg Med Chem Lett21:734-7 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin E2 receptor EP4 subtype |
|---|
| Name: | Prostaglandin E2 receptor EP4 subtype |
|---|
| Synonyms: | PE2R4_HUMAN | PGE receptor EP4 subtype | PGE2 receptor EP4 subtype | PTGER2 | PTGER4 | Prostaglandin E2 receptor | Prostanoid EP4 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 53134.53 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35408 |
|---|
| Residue: | 488 |
|---|
| Sequence: | MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP
SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG
QHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPG
MGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSET
LNLSEKCI
|
|
|
|---|
| BDBM50333730 |
|---|
| n/a |
|---|
| Name | BDBM50333730 |
|---|
| Synonyms: | CHEMBL1644009 | N,5,7-trimethyl-3-(4-(2-(3-tosylureido)ethyl)phenyl)benzo[b]thiophene-2-carboxamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H29N3O4S2 |
|---|
| Mol. Mass. | 535.678 |
|---|
| SMILES | CNC(=O)c1sc2c(C)cc(C)cc2c1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
