| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin L2 |
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| Ligand | BDBM50336478 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_716901 (CHEMBL1670880) |
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| Ki | 1100±n/a nM |
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| Citation |  Severino, RP; Guido, RV; Marques, EF; Brömme, D; da Silva, MF; Fernandes, JB; Andricopulo, AD; Vieira, PC Acridone alkaloids as potent inhibitors of cathepsin V. Bioorg Med Chem19:1477-81 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin L2 |
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| Name: | Cathepsin L2 |
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| Synonyms: | CATL2 | CATL2_HUMAN | CTSL2 | CTSU | CTSV | Cathepsin U | Cathepsin V |
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| Type: | Enzyme |
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| Mol. Mass.: | 37341.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O60911 |
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| Residue: | 334 |
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| Sequence: | MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
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| BDBM50336478 |
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| n/a |
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| Name | BDBM50336478 |
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| Synonyms: | 1,3,5-trihydroxy-4-methoxy-2-(3-methylbut-2-enyl)-10-methyl-9-acridone | CHEMBL463652 | glycocitrine-IV |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21NO5 |
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| Mol. Mass. | 355.3844 |
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| SMILES | [#6]-[#8]-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c2c1n(-[#6])c1c(-[#8])cccc1c2=O |
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| Structure | 
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