| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM33411 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_725038 (CHEMBL1678143) |
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| IC50 | 250±n/a nM |
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| Citation |  Chung, S; Wendeler, M; Rausch, JW; Beilhartz, G; Gotte, M; O'Keefe, BR; Bermingham, A; Beutler, JA; Liu, S; Zhuang, X; Le Grice, SF Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H. Antimicrob Agents Chemother54:3913-21 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 64758.82 |
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| Organism: | Human immunodeficiency virus 2 |
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| Description: | ChEMBL_725038 |
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| Residue: | 560 |
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| Sequence: | MAVAKVEPIKIMLKPGKDGPKLRQWPLTKEKIEALKEICEKMEKEGQLEEAPPTNPYNTP
TFAIKKKDKNKWRMLIDFRELNKVTQDFTEIQLGIPHPAGLAKKRRITVLDVGDAYFSIP
LHEDFRPYTAFTLPSVNNAEPGKRYIYKVLPQGWKGSPAIFQHTMRQVLEPFRKANKDVI
IIQYMDDILIASDRTDLEHDRVILQLKELLNGLGFSTPDEKFQKDPPYHWMGYELWPTKW
KLQKIQLPQKEIWTVNDIQKLVGVLNWAAQLYPGIKTKHLCRLIRGKMTLTEEVQWTELA
EAELEENRIILSQEQEGHYYQEEKELEATVQKDQDNQWTYKIHQEDKILKVGKYAKVKNT
HTNGIRLLAQVVQKIGKEALVIWGRIPKFHLPVEREIWEQWWDNYWQVTWIPDWDFVSTP
PLVRLAFNLVGDPIPGAETFYTDGSCNRQSKEGKAGYVTDRGKDKVKKLEQTTNQQAELE
AFAMALTDSGPKVNIIVDSQYVMGIVASQPTESESKIVNQIIEEMIKKEAIYVAWVPAHK
GIGGNQEVDHLVSQGIRQVL
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| BDBM33411 |
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| n/a |
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| Name | BDBM33411 |
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| Synonyms: | β-Thujaplicinol | hydroxytropolone, 3 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H12O3 |
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| Mol. Mass. | 180.2005 |
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| SMILES | CC(C)c1ccc(O)c(=O)c(O)c1 |
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| Structure | 
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