| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
|---|
| Ligand | BDBM50337881 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_726948 (CHEMBL1686737) |
|---|
| Ki | 61±n/a nM |
|---|
| Citation |  Hughes, AD; Chin, KH; Dunham, SL; Jasper, JR; King, KE; Lee, TW; Mammen, M; Martin, J; Steinfeld, T Discovery of muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist (MABA) dual pharmacology molecules. Bioorg Med Chem Lett21:1354-8 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-2 adrenergic receptor |
|---|
| Name: | Beta-2 adrenergic receptor |
|---|
| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 46461.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P07550 |
|---|
| Residue: | 413 |
|---|
| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
|
|
|
|---|
| BDBM50337881 |
|---|
| n/a |
|---|
| Name | BDBM50337881 |
|---|
| Synonyms: | (R)-1-(9-(2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethylamino)nonyl)piperidin-4-yl biphenyl-2-ylcarbamate | CHEMBL1683936 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C36H49N3O5 |
|---|
| Mol. Mass. | 603.7914 |
|---|
| SMILES | OCc1cc(ccc1O)[C@@H](O)CNCCCCCCCCCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
