| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 2C9 |
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| Ligand | BDBM50337910 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_726958 (CHEMBL1686747) |
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| IC50 | >25000±n/a nM |
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| Citation |  Shao, L; Hewitt, MC; Wang, F; Malcolm, SC; Ma, J; Campbell, JE; Campbell, UC; Engel, SR; Spicer, NA; Hardy, LW; Schreiber, R; Spear, KL; Varney, MA Discovery of N-methyl-1-(1-phenylcyclohexyl)ethanamine, a novel triple serotonin, norepinephrine and dopamine reuptake inhibitor. Bioorg Med Chem Lett21:1434-7 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 2C9 |
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| Name: | Cytochrome P450 2C9 |
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| Synonyms: | (R)-limonene 6-monooxygenase | (S)-limonene 6-monooxygenase | CP2C9_HUMAN | CYP2C10 | CYP2C9 | CYPIIC9 | Cytochrome P450 2C9 (CYP2C9 ) | Cytochrome P450 2C9 (CYP2C9) | P-450MP | P450 MP-4/MP-8 | P450 PB-1 | S-mephenytoin 4-hydroxylase |
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| Type: | Enzyme |
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| Mol. Mass.: | 55636.33 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11712 |
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| Residue: | 490 |
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| Sequence: | MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKV
YGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKW
KEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICS
IIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFM
KSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTE
TTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYID
LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFK
KSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVP
PFYQLCFIPV
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| BDBM50337910 |
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| n/a |
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| Name | BDBM50337910 |
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| Synonyms: | (+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N-methylethanamine | 1-(1-(3,4-dichlorophenyl)cyclohexyl)-N-methylethanamine | CHEMBL1684045 | CHEMBL1684057 | US10562878, Compound 108 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H21Cl2N |
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| Mol. Mass. | 286.24 |
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| SMILES | CNC(C)C1(CCCCC1)c1ccc(Cl)c(Cl)c1 |
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| Structure | 
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