| Reaction Details |
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 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 |
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| Ligand | BDBM50339874 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_740704 (CHEMBL1763766) |
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| IC50 | 2±n/a nM |
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| Citation |  Gustin, DJ; Ma, Z; Min, X; Li, Y; Hedberg, C; Guimaraes, C; Porter, AC; Lindstrom, M; Lester-Zeiner, D; Xu, G; Carlson, TJ; Xiao, S; Meleza, C; Connors, R; Wang, Z; Kayser, F Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors. Bioorg Med Chem Lett21:2492-6 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fatty-acid amide hydrolase 1 |
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| Name: | Fatty-acid amide hydrolase 1 |
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| Synonyms: | Anandamide amidohydrolase | Anandamide amidohydrolase 1 | FAAH | FAAH1 | FAAH1_HUMAN | Fatty Acid Amide Hydrolase (FAAH) | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Oleamide hydrolase 1 |
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| Type: | Protein |
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| Mol. Mass.: | 63071.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O00519 |
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| Residue: | 579 |
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| Sequence: | MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQ
RFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLAD
CETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAV
PFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGG
SIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCE
DMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTL
VPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAF
LVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALD
LNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMK
KSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
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| BDBM50339874 |
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| n/a |
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| Name | BDBM50339874 |
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| Synonyms: | 2-(3-(1-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-yl)piperidin-3-yl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)acetonitrile | CHEMBL1761455 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H24N6S |
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| Mol. Mass. | 464.585 |
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| SMILES | Cc1c(C2CCCN(C2)c2nccc(n2)-c2cc3ccccc3s2)c2cccnc2n1CC#N |
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| Structure | 
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