| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosinase |
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| Ligand | BDBM50264087 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_740266 (CHEMBL1764166) |
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| IC50 | 730±n/a nM |
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| Citation |  Tajima, R; Oozeki, H; Muraoka, S; Tanaka, S; Motegi, Y; Nihei, H; Yamada, Y; Masuoka, N; Nihei, K Synthesis and evaluation of bibenzyl glycosides as potent tyrosinase inhibitors. Eur J Med Chem46:1374-81 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosinase |
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| Name: | Tyrosinase |
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| Synonyms: | LB24-AB | Monophenol monooxygenase | SK29-AB | TYR | TYRO_HUMAN | Tumor rejection antigen AB |
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| Type: | Protein |
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| Mol. Mass.: | 60388.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14679 |
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| Residue: | 529 |
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| Sequence: | MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILL
SNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVR
RNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMH
YYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRD
AEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRN
PGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQS
SMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGH
NRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLG
AAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL
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| BDBM50264087 |
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| n/a |
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| Name | BDBM50264087 |
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| Synonyms: | (2S,2'S,3R,3'R,4S,4'S,5R,5'R)-2,2'-(4-(2,4-dihydroxyphenethyl)-1,3-phenylene)bis(oxy)bis(tetrahydro-2H-pyran-3,4,5-triol) | CHEMBL489989 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30O12 |
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| Mol. Mass. | 510.4878 |
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| SMILES | O[C@@H]1CO[C@@H](Oc2ccc(CCc3ccc(O)cc3O)c(O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)c2)[C@H](O)[C@H]1O |r| |
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| Structure | 
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