| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosinase |
|---|
| Ligand | BDBM50031467 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_740266 (CHEMBL1764166) |
|---|
| IC50 | 7400±n/a nM |
|---|
| Citation |  Tajima, R; Oozeki, H; Muraoka, S; Tanaka, S; Motegi, Y; Nihei, H; Yamada, Y; Masuoka, N; Nihei, K Synthesis and evaluation of bibenzyl glycosides as potent tyrosinase inhibitors. Eur J Med Chem46:1374-81 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tyrosinase |
|---|
| Name: | Tyrosinase |
|---|
| Synonyms: | LB24-AB | Monophenol monooxygenase | SK29-AB | TYR | TYRO_HUMAN | Tumor rejection antigen AB |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 60388.08 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P14679 |
|---|
| Residue: | 529 |
|---|
| Sequence: | MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILL
SNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVR
RNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMH
YYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRD
AEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRN
PGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQS
SMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGH
NRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLG
AAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL
|
|
|
|---|
| BDBM50031467 |
|---|
| n/a |
|---|
| Name | BDBM50031467 |
|---|
| Synonyms: | 5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hydroxy-2-hydroxymethyl-pyran-4-one | CHEMBL287556 | Kojic Acid | US10857082, Kojic acid | US9422261, Kojic acid | US9682910, kojic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C6H6O4 |
|---|
| Mol. Mass. | 142.1094 |
|---|
| SMILES | OCc1cc(=O)c(O)co1 |
|---|
| Structure | 
|
|---|
Search and Browse
