| Reaction Details |
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 | Report a problem with these data |
| Target | Hemagglutinin-neuraminidase |
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| Ligand | BDBM50341451 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_741750 (CHEMBL1769849) |
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| IC50 | 7700000±n/a nM |
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| Citation |  Nishino, R; Ikeda, K; Hayakawa, T; Takahashi, T; Suzuki, T; Sato, M Syntheses of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid analogues modified by N-sulfonylamidino groups at the C-4 position and biological evaluation as inhibitors of human parainfluenza virus type 1. Bioorg Med Chem19:2418-27 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Hemagglutinin-neuraminidase |
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| Name: | Hemagglutinin-neuraminidase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 64031.12 |
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| Organism: | Human parainfluenza virus 1 |
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| Description: | ChEMBL_741750 |
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| Residue: | 575 |
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| Sequence: | MAEKGKTNSSYWSTTRNDNSTVNTYIDTPAGKTHIWLLIATTMHTILSFIIMILCIDLII
KQDTCMKTNIITISSMNESAKTIKETITELIRQEVISRTINIQSSVQSGIPILLNKQSRD
LTQLIEKSCNRQELAQICENTNAIHHADGISPLDPHDFWRCPVGEPLLSDNPNISLLPGP
SLLSGSTTISGCVRLPSLSIGDAIYAYSSNLITQGCADIGKSYQVLQLGYISLNSDMYPD
LNPVISHTYDINDNRKSCSVIAAGTRGYQLCSLPTVNETTDYSSEGIEDLVFDILDLKGK
TKSHRYKNEDITFDHPFSAMYPSVGSGIKIENTLIFLGYGGLTTPLQGDTKCVTNRCANV
NQSVCNDALKITWRLKKRQVNVLIRINNYLSDRPKIVVETIPITQNYLGAEGRLLKLGKK
IYIYTRSSGWHSHLQIGSLDINNPMTIKWAPHEVLSRPGNQDCNWYNRCPRECISGVYTD
AYPLSPDAVNVATTTLYANTSRVNPTIMYSNTSEIINMLRLKNVQLEAAYTTTSCITHFG
KGYCFHIVEINQTSLNTLQPMLFKTSIPKICKITS
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| BDBM50341451 |
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| n/a |
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| Name | BDBM50341451 |
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| Synonyms: | 5-Acetamido-2,6-anhydro-3,5-dideoxy-4-O-[3-(isopropylamino)-3-(tosylimino)-propoxy]-D-glycero-D-galacto-non-2-enonic acid | CHEMBL1767330 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H35N3O10S |
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| Mol. Mass. | 557.614 |
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| SMILES | CC(C)N=C(CCO[C@H]1C=C(O[C@@H]([C@H](O)[C@H](O)CO)[C@@H]1NC(C)=O)C(O)=O)NS(=O)(=O)c1ccc(C)cc1 |r,w:3.2,c:9| |
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| Structure | 
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