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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 1 | ||
| Ligand | BDBM50342730 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_744205 (CHEMBL1771962) | ||
| Ki | 38±n/a nM | ||
| Citation |  Griffith, DA; Hargrove, DM; Maurer, TS; Blum, CA; De Lombaert, S; Inthavongsay, JK; Klade, LE; Mack, CM; Rose, CR; Sanders, MJ; Carpino, PA Discovery and evaluation of pyrazolo[1,5-a]pyrimidines as neuropeptide Y1 receptor antagonists. Bioorg Med Chem Lett21:2641-5 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 1 | |||
| Name: | Neuropeptide Y receptor type 1 | ||
| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 44399.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | NPY-Y1 NPY1R HUMAN::P25929 | ||
| Residue: | 384 | ||
| Sequence: |
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| BDBM50342730 | |||
| n/a | |||
| Name | BDBM50342730 | ||
| Synonyms: | CHEMBL1771257 | N1-cyclopentyl-N2-(3-(2,6-dichlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl)ethane-1,2-diamine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H25Cl2N5 | ||
| Mol. Mass. | 418.363 | ||
| SMILES | Cc1nn2c(NCCNC3CCCC3)cc(C)nc2c1-c1c(Cl)cccc1Cl |(-9.32,-14.84,;-7.78,-14.84,;-6.87,-13.59,;-5.4,-14.07,;-4.07,-13.31,;-4.08,-11.77,;-2.74,-10.99,;-1.41,-11.76,;-.08,-10.99,;1.12,-11.96,;1.04,-13.49,;2.48,-14.04,;3.45,-12.84,;2.61,-11.55,;-2.74,-14.07,;-2.73,-15.62,;-1.4,-16.39,;-4.07,-16.39,;-5.4,-15.62,;-6.87,-16.1,;-7.63,-17.44,;-9.17,-17.44,;-9.95,-16.12,;-9.92,-18.78,;-9.14,-20.11,;-7.59,-20.09,;-6.84,-18.75,;-5.3,-18.73,)| | ||
| Structure | 
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