Reaction Details |
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Target | Uracil-DNA glycosylase |
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Ligand | BDBM50343395 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_747132 (CHEMBL1777498) |
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IC50 | 34100±n/a nM |
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Citation | Nuth, M; Huang, L; Saw, YL; Schormann, N; Chattopadhyay, D; Ricciardi, RP Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4. J Med Chem54:3260-7 (2011) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Uracil-DNA glycosylase |
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Name: | Uracil-DNA glycosylase |
Synonyms: | OPG116 | UDG | UNG | UNG_VACCW |
Type: | PROTEIN |
Mol. Mass.: | 25071.48 |
Organism: | Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR)) |
Description: | ChEMBL_747132 |
Residue: | 218 |
Sequence: | MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNK
RVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWN
YYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDYSNIRAKLESPVTTIVGY
HPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
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BDBM50343395 |
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n/a |
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Name | BDBM50343395 |
Synonyms: | 10-(cyclohexylamino)-12-[(2-hydroxyethyl)amino]-15-oxa-14-azatetracyclohexadeca-1(16),2,4,6,9,11,13-heptaen-8-one | CHEMBL1774936 |
Type | Small organic molecule |
Emp. Form. | C22H25N3O3 |
Mol. Mass. | 379.4522 |
SMILES | OCCN=C1CC(NC2CCCCC2)c2c(O)c3ccccc3c3onc1c23 |w:3.2| |
Structure |
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