Compile Data Set for Download or QSAR

Found 111 hits with Last Name = 'ricciardi' and Initial = 'rp'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208055 (3-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol-...) Show SMILES Cc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c(CC(N)=O)[nH]c2c1 Show InChI InChI=1S/C17H14Cl2N2OS/c1-9-2-3-13-14(4-9)21-15(8-16(20)22)17(13)23-12-6-10(18)5-11(19)7-12/h2-7,21H,8H2,1H3,(H2,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208056 (2-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol-...) Show SMILES Cc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c([nH]c2c1)C(N)=O Show InChI InChI=1S/C16H12Cl2N2OS/c1-8-2-3-12-13(4-8)20-14(16(19)21)15(12)22-11-6-9(17)5-10(18)7-11/h2-7,20H,1H3,(H2,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208057 ( 4-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol...) Show SMILES Cc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c(CCCC(N)=O)[nH]c2c1 Show InChI InChI=1S/C19H18Cl2N2OS/c1-11-5-6-15-17(7-11)23-16(3-2-4-18(22)24)19(15)25-14-9-12(20)8-13(21)10-14/h5-10,23H,2-4H2,1H3,(H2,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	208	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208058 (3-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol-...) Show SMILES Cc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c(CCC(N)=O)[nH]c2c1 Show InChI InChI=1S/C18H16Cl2N2OS/c1-10-2-3-14-16(6-10)22-15(4-5-17(21)23)18(14)24-13-8-11(19)7-12(20)9-13/h2-3,6-9,22H,4-5H2,1H3,(H2,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	244	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196131 (US9211296, Table 7, Compd: 1) Show SMILES CCN1CCN(CC1)c1ccc(Nc2ccnc3cc4ccccc4cc23)cc1 Show InChI InChI=1S/C25H26N4/c1-2-28-13-15-29(16-14-28)22-9-7-21(8-10-22)27-24-11-12-26-25-18-20-6-4-3-5-19(20)17-23(24)25/h3-12,17-18H,2,13-16H2,1H3,(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196132 (US9211296, Table 7, Compd: 2) Show SMILES BrCc1ccc(cc1)-c1noc(n1)-c1ccncc1 Show InChI InChI=1S/C14H10BrN3O/c15-9-10-1-3-11(4-2-10)13-17-14(19-18-13)12-5-7-16-8-6-12/h1-8H,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196133 (US9211296, Table 7, Compd: 3) Show SMILES CN(C)c1ccc(cc1)-c1cccc([o+]1)-c1ccc(cc1)N(C)C Show InChI InChI=1S/C21H23N2O/c1-22(2)18-12-8-16(9-13-18)20-6-5-7-21(24-20)17-10-14-19(15-11-17)23(3)4/h5-15H,1-4H3/q+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196134 (US9211296, Table 7, Compd: 4) Show SMILES CC[n+]1cc(\C=C2/SC=CN2C)c(C)c2cc(OC)c3ccccc3c12 |c:8| Show InChI InChI=1S/C22H23N2OS/c1-5-24-14-16(12-21-23(3)10-11-26-21)15(2)19-13-20(25-4)17-8-6-7-9-18(17)22(19)24/h6-14H,5H2,1-4H3/q+1/b21-12-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196135 (US9211296, Table 7, Compd: 5) Show SMILES CCOC(=O)CCc1c(CC(=O)OCC)cnc1\C=N\O Show InChI InChI=1S/C14H19N2O5/c1-3-20-13(17)6-5-11-10(7-14(18)21-4-2)8-15-12(11)9-16-19/h8-9,19H,3-7H2,1-2H3/b16-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196136 (US9211296, Table 7, Compd: 6) Show SMILES COc1ccc2N(C)\C(=C\c3sc4ccccc4[n+]3C)C=Cc2c1 |c:22| Show InChI InChI=1S/C20H19N2OS/c1-21-15(9-8-14-12-16(23-3)10-11-17(14)21)13-20-22(2)18-6-4-5-7-19(18)24-20/h4-13H,1-3H3/q+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM51365 (1-N-benzo[g]quinolin-4-yl-4-N-propan-2-ylbenzene-1...) Show SMILES CC(C)Nc1ccc(Nc2ccnc3cc4ccccc4cc23)cc1 Show InChI InChI=1S/C22H21N3/c1-15(2)24-18-7-9-19(10-8-18)25-21-11-12-23-22-14-17-6-4-3-5-16(17)13-20(21)22/h3-15,24H,1-2H3,(H,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196137 (US9211296, Table 7, Compd: 8) Show SMILES CCOC(=O)c1cnc2c(C)c(C)ccc2c1NCCCN(C)C Show InChI InChI=1S/C19H27N3O2/c1-6-24-19(23)16-12-21-17-14(3)13(2)8-9-15(17)18(16)20-10-7-11-22(4)5/h8-9,12H,6-7,10-11H2,1-5H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM33154 (4-[(2-benzoxybenzyl)amino]phenol | 4-[(2-phenylmet...) Show SMILES Oc1ccc(NCc2ccccc2OCc2ccccc2)cc1 Show InChI InChI=1S/C20H19NO2/c22-19-12-10-18(11-13-19)21-14-17-8-4-5-9-20(17)23-15-16-6-2-1-3-7-16/h1-13,21-22H,14-15H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196138 (US9211296, Table 7, Compd: 9) Show SMILES CC1=CC(C)(C)N=C(Nc2nc(C)c3cc(C)cc(C)c3n2)N1 |t:1,6| Show InChI InChI=1S/C18H23N5/c1-10-7-11(2)15-14(8-10)13(4)20-16(21-15)22-17-19-12(3)9-18(5,6)23-17/h7-9H,1-6H3,(H2,19,20,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM69679 (Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...) Show SMILES CN(C)CCc1cc2OCOc2c2c1ccc1ccccc21 Show InChI InChI=1S/C19H19NO2/c1-20(2)10-9-14-11-17-19(22-12-21-17)18-15-6-4-3-5-13(15)7-8-16(14)18/h3-8,11H,9-10,12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM51312 (3-[(8,9-dimethoxy-2-phenyl-[1,2,4]triazolo[1,5-c]q...) Show SMILES CCN(CC)CCCNc1nc2cc(OC)c(OC)cc2c2nc(nn12)-c1ccccc1 Show InChI InChI=1S/C24H30N6O2/c1-5-29(6-2)14-10-13-25-24-26-19-16-21(32-4)20(31-3)15-18(19)23-27-22(28-30(23)24)17-11-8-7-9-12-17/h7-9,11-12,15-16H,5-6,10,13-14H2,1-4H3,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196139 (US9211296, Table 7, Compd: 12) Show SMILES Cc1cc(NCCN2CCCCC2)c2ccc3ccccc3c2n1 Show InChI InChI=1S/C21H25N3/c1-16-15-20(22-11-14-24-12-5-2-6-13-24)19-10-9-17-7-3-4-8-18(17)21(19)23-16/h3-4,7-10,15H,2,5-6,11-14H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196140 (US9211296, Table 7, Compd: 13) Show SMILES OC(CN1CCNCC1)Cn1c2ccc(Br)cc2c2cc(Br)ccc12 Show InChI InChI=1S/C19H21Br2N3O/c20-13-1-3-18-16(9-13)17-10-14(21)2-4-19(17)24(18)12-15(25)11-23-7-5-22-6-8-23/h1-4,9-10,15,22,25H,5-8,11-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196141 (US9211296, Table 7, Compd: 14) Show SMILES CN(C)CC\N=c1/cc(oc2ccc(Cl)cc12)-c1ccccc1 Show InChI InChI=1S/C19H19ClN2O/c1-22(2)11-10-21-17-13-19(14-6-4-3-5-7-14)23-18-9-8-15(20)12-16(17)18/h3-9,12-13H,10-11H2,1-2H3/b21-17+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208048 ( 3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indole-2...) Show SMILES Cc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H11Cl2NO2S/c1-8-2-3-12-13(4-8)19-14(16(20)21)15(12)22-11-6-9(17)5-10(18)7-11/h2-7,19H,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196142 (US9211296, Table 7, Compd: 15) Show SMILES CC1CCCC(C)N1CCNc1nc2ccccc2c2nc(nn12)-c1ccccc1 Show InChI InChI=1S/C24H28N6/c1-17-9-8-10-18(2)29(17)16-15-25-24-26-21-14-7-6-13-20(21)23-27-22(28-30(23)24)19-11-4-3-5-12-19/h3-7,11-14,17-18H,8-10,15-16H2,1-2H3,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196143 (US9211296, Table 7, Compd: 16) Show SMILES OC(=O)c1ccc(CS(=O)(=O)c2ccccc2)o1 Show InChI InChI=1S/C12H10O5S/c13-12(14)11-7-6-9(17-11)8-18(15,16)10-4-2-1-3-5-10/h1-7H,8H2,(H,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196144 (US9211296, Table 7, Compd: 17) Show SMILES COc1ccc2nc(NC(N)=N)nc(C)c2c1 Show InChI InChI=1S/C11H13N5O/c1-6-8-5-7(17-2)3-4-9(8)15-11(14-6)16-10(12)13/h3-5H,1-2H3,(H4,12,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208049 (3-((3,5-Dichlorophenyl)thio)-6-ethyl-1H-indole-2-c...) Show SMILES CCc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C17H13Cl2NO2S/c1-2-9-3-4-13-14(5-9)20-15(17(21)22)16(13)23-12-7-10(18)6-11(19)8-12/h3-8,20H,2H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208051 (6-Methyl-3-(phenylthio)-1H-indole-2-carboxylate |...) Show SMILES COC(=O)c1[nH]c2cc(C)ccc2c1Sc1ccccc1 Show InChI InChI=1S/C17H15NO2S/c1-11-8-9-13-14(10-11)18-15(17(19)20-2)16(13)21-12-6-4-3-5-7-12/h3-10,18H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196146 (US9211296, Table 7, Compd: 19) Show SMILES CN(C)CCN(Cc1ccco1)C(=O)c1cc2c(Cl)nc3ccc(C)cc3c2s1 Show InChI InChI=1S/C22H22ClN3O2S/c1-14-6-7-18-16(11-14)20-17(21(23)24-18)12-19(29-20)22(27)26(9-8-25(2)3)13-15-5-4-10-28-15/h4-7,10-12H,8-9,13H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196145 (US9211296, Table 7, Compd: 18) Show SMILES Clc1nc2ccccc2c2sc(cc12)C(=O)NCCCN1CCCC1 Show InChI InChI=1S/C19H20ClN3OS/c20-18-14-12-16(19(24)21-8-5-11-23-9-3-4-10-23)25-17(14)13-6-1-2-7-15(13)22-18/h1-2,6-7,12H,3-5,8-11H2,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196150 (US9211296, Table 6, 4) Show SMILES Cc1csc2c(ncnc12)N1CCN(CC1)C(=O)NC(C)(C)C Show InChI InChI=1S/C16H23N5OS/c1-11-9-23-13-12(11)17-10-18-14(13)20-5-7-21(8-6-20)15(22)19-16(2,3)4/h9-10H,5-8H2,1-4H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208054 (4-Methyl-3-((2,4,5-trichlorophenyl)thio)-1H-indole...) Show SMILES Cc1cccc2[nH]c(C(O)=O)c(Sc3cc(Cl)c(Cl)cc3Cl)c12 Show InChI InChI=1S/C16H10Cl3NO2S/c1-7-3-2-4-11-13(7)15(14(20-11)16(21)22)23-12-6-9(18)8(17)5-10(12)19/h2-6,20H,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208038 (Methyl 3-((4-chlorophenyl)thio)-6-methyl-1H-indole...) Show SMILES COC(=O)c1[nH]c2cc(C)ccc2c1Sc1ccc(Cl)cc1 Show InChI InChI=1S/C17H14ClNO2S/c1-10-3-8-13-14(9-10)19-15(17(20)21-2)16(13)22-12-6-4-11(18)5-7-12/h3-9,19H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208040 (Methyl 3-((4-chlorophenyl)thio)-4-methyl-1H-indole...) Show SMILES COC(=O)c1[nH]c2cccc(C)c2c1Sc1ccc(Cl)cc1 Show InChI InChI=1S/C17H14ClNO2S/c1-10-4-3-5-13-14(10)16(15(19-13)17(20)21-2)22-12-8-6-11(18)7-9-12/h3-9,19H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208053 (7-Methyl-3-((2,4,5-trichlorophenyl)thio)-1H-indole...) Show SMILES Cc1cccc2c(Sc3cc(Cl)c(Cl)cc3Cl)c([nH]c12)C(O)=O Show InChI InChI=1S/C16H10Cl3NO2S/c1-7-3-2-4-8-13(7)20-14(16(21)22)15(8)23-12-6-10(18)9(17)5-11(12)19/h2-6,20H,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208039 (Methyl 3-((4-chlorophenyl)thio)-7-methyl-1H-indole...) Show SMILES COC(=O)c1[nH]c2c(C)cccc2c1Sc1ccc(Cl)cc1 Show InChI InChI=1S/C17H14ClNO2S/c1-10-4-3-5-13-14(10)19-15(17(20)21-2)16(13)22-12-8-6-11(18)7-9-12/h3-9,19H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208052 (6-Methyl-3-((2,4,5-trichlorophenyl)thio)-1H-indole...) Show SMILES Cc1ccc2c(Sc3cc(Cl)c(Cl)cc3Cl)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H10Cl3NO2S/c1-7-2-3-8-12(4-7)20-14(16(21)22)15(8)23-13-6-10(18)9(17)5-11(13)19/h2-6,20H,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196153 (US9211296, Table 6, 7) Show SMILES Cc1c(cccc1C(O)=O)\N=C\c1cc(Br)cc(Br)c1Br Show InChI InChI=1S/C15H10Br3NO2/c1-8-11(15(20)21)3-2-4-13(8)19-7-9-5-10(16)6-12(17)14(9)18/h2-7H,1H3,(H,20,21)/b19-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196155 (US9211296, Table 6, 9) Show SMILES OC(=O)c1ccccc1NC(=O)OCC1c2ccccc2-c2ccccc12 Show InChI InChI=1S/C22H17NO4/c24-21(25)18-11-5-6-12-20(18)23-22(26)27-13-19-16-9-3-1-7-14(16)15-8-2-4-10-17(15)19/h1-12,19H,13H2,(H,23,26)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196152 (US9211296, Table 6, 6) Show SMILES Cc1cc(\N=C\c2cc(Cl)cc(Cl)c2O)no1 Show InChI InChI=1S/C11H8Cl2N2O2/c1-6-2-10(15-17-6)14-5-7-3-8(12)4-9(13)11(7)16/h2-5,16H,1H3/b14-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196158 (US9211296, Table 6, 12) Show SMILES N=C1S\C(=C\c2ccco2)C(=O)N1c1nccs1 Show InChI InChI=1S/C11H7N3O2S2/c12-10-14(11-13-3-5-17-11)9(15)8(18-10)6-7-2-1-4-16-7/h1-6,12H/b8-6+,12-10?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208043 (6-Methyl-3-((4-(trifluoromethyl)phenyl)thio)-1H-in...) Show SMILES Cc1ccc2c(Sc3ccc(cc3)C(F)(F)F)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C17H12F3NO2S/c1-9-2-7-12-13(8-9)21-14(16(22)23)15(12)24-11-5-3-10(4-6-11)17(18,19)20/h2-8,21H,1H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208045 (3-((3,4-Dichlorophenyl)thio)-6-methyl-1H-indole-2-...) Show SMILES Cc1ccc2c(Sc3ccc(Cl)c(Cl)c3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H11Cl2NO2S/c1-8-2-4-10-13(6-8)19-14(16(20)21)15(10)22-9-3-5-11(17)12(18)7-9/h2-7,19H,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343395 (10-(cyclohexylamino)-12-[(2-hydroxyethyl)amino]-15...) Show SMILES OCCN=C1CC(NC2CCCCC2)c2c(O)c3ccccc3c3onc1c23 |w:3.2| Show InChI InChI=1S/C22H25N3O3/c26-11-10-23-17-12-16(24-13-6-2-1-3-7-13)18-19-20(17)25-28-22(19)15-9-5-4-8-14(15)21(18)27/h4-5,8-9,13,16,24,26-27H,1-3,6-7,10-12H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208046 (3-((3,4-Dichlorophenyl)thio)-7-methyl-1H-indole-2-...) Show SMILES Cc1cccc2c(Sc3ccc(Cl)c(Cl)c3)c([nH]c12)C(O)=O Show InChI InChI=1S/C16H11Cl2NO2S/c1-8-3-2-4-10-13(8)19-14(16(20)21)15(10)22-9-5-6-11(17)12(18)7-9/h2-7,19H,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208032 (3-((4-Chlorophenyl)thio)-6-ethyl-1H-indole-2-carbo...) Show SMILES CCc1ccc2c(Sc3ccc(Cl)cc3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C17H14ClNO2S/c1-2-10-3-8-13-14(9-10)19-15(17(20)21)16(13)22-12-6-4-11(18)5-7-12/h3-9,19H,2H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208044 (3-((2,4-Dichlorophenyl)thio)-6-methyl-1H-indole-2-...) Show SMILES Cc1ccc2c(Sc3ccc(Cl)cc3Cl)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H11Cl2NO2S/c1-8-2-4-10-12(6-8)19-14(16(20)21)15(10)22-13-5-3-9(17)7-11(13)18/h2-7,19H,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM80984 (4-chloranyl-2-(5-chloranyl-2-oxidanyl-phenyl)sulfa...) Show SMILES Oc1ccc(Cl)cc1Sc1cc(Cl)ccc1O Show InChI InChI=1S/C12H8Cl2O2S/c13-7-1-3-9(15)11(5-7)17-12-6-8(14)2-4-10(12)16/h1-6,15-16H	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208037 (Methyl 3-((4-chlorophenyl)thio)-1-ethyl-5-methyl-1...) Show SMILES CCn1c(C(=O)OC)c(Sc2ccc(Cl)cc2)c2cc(C)ccc12 Show InChI InChI=1S/C19H18ClNO2S/c1-4-21-16-10-5-12(2)11-15(16)18(17(21)19(22)23-3)24-14-8-6-13(20)7-9-14/h5-11H,4H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208031 (6-Fluoro-3-((4-chlorophenyl)thio)-1H-indole-2-carb...) Show SMILES OC(=O)c1[nH]c2cc(F)ccc2c1Sc1ccc(Cl)cc1 Show InChI InChI=1S/C15H9ClFNO2S/c16-8-1-4-10(5-2-8)21-14-11-6-3-9(17)7-12(11)18-13(14)15(19)20/h1-7,18H,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208047 (3-((3,4-Dichlorophenyl)thio)-6-ethyl-1H-indole-2-c...) Show SMILES CCc1ccc2c(Sc3ccc(Cl)c(Cl)c3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C17H13Cl2NO2S/c1-2-9-3-5-11-14(7-9)20-15(17(21)22)16(11)23-10-4-6-12(18)13(19)8-10/h3-8,20H,2H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair
DNA polymerase (Vaccinia virus (strain WR))	BDBM196157 (US9211296, Table 6, 11 | US9233921, 1) Show SMILES Cc1ccc2c(Sc3ccc(Cl)cc3)c([nH]c2c1)C(O)=O Show InChI InChI=1S/C16H12ClNO2S/c1-9-2-7-12-13(8-9)18-14(16(19)20)15(12)21-11-5-3-10(17)4-6-11/h2-8,18H,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	7.4	37
The Trustees of the University of Pennsylvania US Patent					Assay Description A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...				US Patent US9211296 (2015) BindingDB Entry DOI: 10.7270/Q2G73CHS
					More data for this Ligand-Target Pair
Uracil-DNA glycosylase (Vaccinia virus (strain Copenhagen) (VACV))	BDBM208050 (3-((3,5-Dichlorophenyl)thio)-1H-indole-2-carboxyli...) Show SMILES OC(=O)c1[nH]c2ccccc2c1Sc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C15H9Cl2NO2S/c16-8-5-9(17)7-10(6-8)21-14-11-3-1-2-4-12(11)18-13(14)15(19)20/h1-7,18H,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	37
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA US Patent					Assay Description African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...				US Patent US9233921 (2016) BindingDB Entry DOI: 10.7270/Q2222SM8
					More data for this Ligand-Target Pair

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