BDBM50343395 10-(cyclohexylamino)-12-[(2-hydroxyethyl)amino]-15-oxa-14-azatetracyclohexadeca-1(16),2,4,6,9,11,13-heptaen-8-one::CHEMBL1774936

SMILES: OCCN=C1CC(NC2CCCCC2)c2c(O)c3ccccc3c3onc1c23

InChI Key: InChIKey=XILICUUQNVFKJK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343395   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343395 (10-(cyclohexylamino)-12-[(2-hydroxyethyl)amino]-15...) Show SMILES OCCN=C1CC(NC2CCCCC2)c2c(O)c3ccccc3c3onc1c23 |w:3.2| Show InChI InChI=1S/C22H25N3O3/c26-11-10-23-17-12-16(24-13-6-2-1-3-7-13)18-19-20(17)25-28-22(19)15-9-5-4-8-14(15)21(18)27/h4-5,8-9,13,16,24,26-27H,1-3,6-7,10-12H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair