Reaction Details |
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Target | Uracil-DNA glycosylase |
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Ligand | BDBM208049 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Viral Plaque Reduction Assay |
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Temperature | 310.15±n/a K |
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IC50 | 9000±n/a nM |
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Comments | extracted |
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Citation | Ricciardi, RP; Nuth, M Potent poxvirus inhibitor US Patent US9233921 Publication Date 1/12/2016 |
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More Info.: | Get all data from this article, Assay Method |
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Uracil-DNA glycosylase |
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Name: | Uracil-DNA glycosylase |
Synonyms: | OPG116 | UNG | UNG_VACCC | vaccinia virus D4/A20 |
Type: | n/a |
Mol. Mass.: | 25083.53 |
Organism: | Vaccinia virus (strain Copenhagen) (VACV) |
Description: | P20536 |
Residue: | 218 |
Sequence: | MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNK
RVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWN
YYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDFSNIRAKLESPVTTIVGY
HPAARDRQFEKDRSFEIINVLLELDNKVPINWAQGFIY
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BDBM208049 |
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n/a |
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Name | BDBM208049 |
Synonyms: | 3-((3,5-Dichlorophenyl)thio)-6-ethyl-1H-indole-2-carboxylic acid | US9233921, 25 |
Type | Small organic molecule |
Emp. Form. | C17H13Cl2NO2S |
Mol. Mass. | 366.262 |
SMILES | CCc1ccc2c(Sc3cc(Cl)cc(Cl)c3)c([nH]c2c1)C(O)=O |
Structure |
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