Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetUracil-DNA glycosylase
LigandBDBM33154
Substrate/Competitorn/a
Meas. Tech.ChEMBL_747132 (CHEMBL1777498)
IC50 5100±n/a nM
Citation Nuth, MHuang, LSaw, YLSchormann, NChattopadhyay, DRicciardi, RP Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4. J Med Chem54:3260-7 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Uracil-DNA glycosylase
Name:Uracil-DNA glycosylase
Synonyms:OPG116 | UDG | UNG | UNG_VACCW
Type:PROTEIN
Mol. Mass.:25071.48
Organism:Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR))
Description:ChEMBL_747132
Residue:218
Sequence:
MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNK
RVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWN
YYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDYSNIRAKLESPVTTIVGY
HPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM33154
n/a
NameBDBM33154
Synonyms:4-[(2-benzoxybenzyl)amino]phenol | 4-[(2-phenylmethoxyphenyl)methylamino]phenol | 4-{[2-(benzyloxy)benzyl]amino}phenol | MLS000704391 | SMR000231540 | US10112895, Compound 10 | cid_833990
TypeSmall organic molecule
Emp. Form.C20H19NO2
Mol. Mass.305.3704
SMILESOc1ccc(NCc2ccccc2OCc2ccccc2)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: