| Reaction Details |
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 | Report a problem with these data |
| Target | Uracil-DNA glycosylase |
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| Ligand | BDBM50343400 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_747132 (CHEMBL1777498) |
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| IC50 | 137600±n/a nM |
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| Citation |  Nuth, M; Huang, L; Saw, YL; Schormann, N; Chattopadhyay, D; Ricciardi, RP Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4. J Med Chem54:3260-7 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Uracil-DNA glycosylase |
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| Name: | Uracil-DNA glycosylase |
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| Synonyms: | OPG116 | UDG | UNG | UNG_VACCW |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25071.48 |
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| Organism: | Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR)) |
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| Description: | ChEMBL_747132 |
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| Residue: | 218 |
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| Sequence: | MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNK
RVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWN
YYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDYSNIRAKLESPVTTIVGY
HPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
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| BDBM50343400 |
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| n/a |
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| Name | BDBM50343400 |
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| Synonyms: | (4-tert-butyl-6-{2-methyl-5H,6H-pyrazolo[1,5-c]quinazolin-5-yl}benzene-1,3-diol | CHEMBL1513961 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23N3O2 |
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| Mol. Mass. | 349.4262 |
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| SMILES | Cc1cc2-c3ccccc3NC(c3cc(c(O)cc3O)C(C)(C)C)n2n1 |
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| Structure | 
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