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TargetUracil-DNA glycosylase
LigandBDBM50343403
Substrate/Competitorn/a
Meas. Tech.ChEMBL_747132 (CHEMBL1777498)
IC50 168600±n/a nM
Citation Nuth, MHuang, LSaw, YLSchormann, NChattopadhyay, DRicciardi, RP Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4. J Med Chem54:3260-7 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Uracil-DNA glycosylase
Name:Uracil-DNA glycosylase
Synonyms:OPG116 | UDG | UNG | UNG_VACCW
Type:PROTEIN
Mol. Mass.:25071.48
Organism:Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR))
Description:ChEMBL_747132
Residue:218
Sequence:
MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNK
RVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWN
YYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDYSNIRAKLESPVTTIVGY
HPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
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BDBM50343403
n/a
NameBDBM50343403
Synonyms:4-methoxy-N-(1-(2-(4-methoxyphenoxy)ethyl)-1H-benzo[d]imidazol-2-yl)benzamide | CHEMBL1592872
TypeSmall organic molecule
Emp. Form.C24H23N3O4
Mol. Mass.417.4571
SMILESCOc1ccc(OCCn2c(NC(=O)c3ccc(OC)cc3)nc3ccccc23)cc1
Structure
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