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TargetUracil-DNA glycosylase
LigandBDBM50343407
Substrate/Competitorn/a
Meas. Tech.ChEMBL_747132 (CHEMBL1777498)
IC50>200000±n/a nM
Citation Nuth, MHuang, LSaw, YLSchormann, NChattopadhyay, DRicciardi, RP Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4. J Med Chem54:3260-7 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Uracil-DNA glycosylase
Name:Uracil-DNA glycosylase
Synonyms:OPG116 | UDG | UNG | UNG_VACCW
Type:PROTEIN
Mol. Mass.:25071.48
Organism:Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR))
Description:ChEMBL_747132
Residue:218
Sequence:
MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNK
RVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWN
YYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDYSNIRAKLESPVTTIVGY
HPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
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  Blast E-value cutoff:
BDBM50343407
n/a
NameBDBM50343407
Synonyms:2-(3-(3,4-dimethoxystyryl)-1-phenyl-1H-1,2,4-triazol-5-yl)phenol | CHEMBL1599653
TypeSmall organic molecule
Emp. Form.C24H21N3O3
Mol. Mass.399.4418
SMILESCOc1ccc(\C=C\c2nc(-c3ccccc3O)n(n2)-c2ccccc2)cc1OC
Structure
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