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TargetVoltage-gated potassium channel beta subunit Mink
LigandBDBM50343721
Substrate/Competitorn/a
Meas. Tech.ChEMBL_746072
IC50>9000±n/a nM
Citation Wang LHubert JALee SJPan JQian SReitman MLStrack AMWeingarth DTMacNeil DJWeber AEEdmondson SD Discovery of pyrimidine carboxamides as potent and selective CCK1 receptor agonists. Bioorg Med Chem Lett 21:2911-5 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Voltage-gated potassium channel beta subunit Mink
Name:Voltage-gated potassium channel beta subunit Mink
Synonyms:Delayed rectifier potassium channel subunit IsK | IKs producing slow voltage-gated potassium channel subunit beta Mink | KCNQ1(Kv7.1)/KCNE1(MinK) | Minimal potassium channel | Voltage-gated potassium channel, IKs
Type:PROTEIN
Mol. Mass.:14676.11
Organism:Homo sapiens (Human)
Description:ChEMBL_1456351
Residue:129
Sequence:
MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG
IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT
HLPETKPSP
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  Blast E-value cutoff:
BDBM50343721
n/a
NameBDBM50343721
Synonyms:3-(4-(4-(2-fluoro-4-methylphenyl)-5-(4-methoxyphenyl)pyrimidine-2-carbonyl)piperazin-1-yl)-1-naphthoic acid | CHEMBL1774043
TypeSmall organic molecule
Emp. Form.C34H29FN4O4
Mol. Mass.576.6169
SMILESCOc1ccc(cc1)-c1cnc(nc1-c1ccc(C)cc1F)C(=O)N1CCN(CC1)c1cc(C(O)=O)c2ccccc2c1
Structure
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