| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
|---|
| Ligand | BDBM50347783 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_756378 (CHEMBL1805404) |
|---|
| EC50 | 8±n/a nM |
|---|
| Citation |  Congreve, M; Langmead, CJ; Mason, JS; Marshall, FH Progress in structure based drug design for G protein-coupled receptors. J Med Chem54:4283-311 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M1 |
|---|
| Name: | Muscarinic acetylcholine receptor M1 |
|---|
| Synonyms: | ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 51442.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P11229 |
|---|
| Residue: | 460 |
|---|
| Sequence: | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
|
|
|
|---|
| BDBM50347783 |
|---|
| n/a |
|---|
| Name | BDBM50347783 |
|---|
| Synonyms: | CHEMBL1223753 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H24FN3O2 |
|---|
| Mol. Mass. | 333.4005 |
|---|
| SMILES | Cc1cc2n(C3CCN(CC3)C3CCOCC3)c(=O)[nH]c2cc1F |
|---|
| Structure | 
|
|---|
Search and Browse
