| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
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| Ligand | BDBM50348427 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_755354 (CHEMBL1804510) |
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| Ki | 116700±n/a nM |
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| Citation |  Jozwiak, K; Woo, AY; Tanga, MJ; Toll, L; Jimenez, L; Kozocas, JA; Plazinska, A; Xiao, RP; Wainer, IW Comparative molecular field analysis of fenoterol derivatives: A platform towards highly selective and effective beta(2)-adrenergic receptor agonists. Bioorg Med Chem18:728-36 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-1 adrenergic receptor |
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| Name: | Beta-1 adrenergic receptor |
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| Synonyms: | ADRB1R, B1AR | ADRB1_RAT | Adrb1 | Adrb1r | Adrenergic receptor beta | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 | adrenergic Beta1,2 |
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| Type: | Protein |
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| Mol. Mass.: | 50486.84 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P18090 |
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| Residue: | 466 |
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| Sequence: | MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAG
MGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRP
SRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSA
FNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDD
DDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
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| BDBM50348427 |
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| n/a |
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| Name | BDBM50348427 |
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| Synonyms: | CHEMBL1800960 | US9492405, 49 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H23NO4 |
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| Mol. Mass. | 317.3795 |
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| SMILES | CC[C@@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |r| |
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| Structure | 
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