| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Proprotein convertase subtilisin/kexin type 7 |
|---|
| Ligand | BDBM50343352 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_760496 (CHEMBL1815481) |
|---|
| IC50 | 24590±n/a nM |
|---|
| Citation |  de Oliveira, CM; Silva, GH; Regasini, LO; Flausino, O; López, SN; Abissi, BM; Berlinck, RG; Sette, LD; Bonugli-Santos, RC; Rodrigues, A; Bolzani, Vda S; Araujo, AR Xylarenones C-E from an endophytic fungus isolated from Alibertia macrophylla. J Nat Prod74:1353-7 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Proprotein convertase subtilisin/kexin type 7 |
|---|
| Name: | Proprotein convertase subtilisin/kexin type 7 |
|---|
| Synonyms: | LPC | Lymphoma proprotein convertase | PC7 | PC8 | PCSK7 | PCSK7_HUMAN | Prohormone convertase PC7 | Proprotein convertase PC7 | Proprotein convertase subtilisin/kexin type 7 | SPC7 | Subtilisin/kexin type 7 | Subtilisin/kexin-like protease PC7 | hPC8 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 86233.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1290739 |
|---|
| Residue: | 785 |
|---|
| Sequence: | MPKGRQKVPHLDAPLGLPTCLWLELAGLFLLVPWVMGLAGTGGPDGQGTGGPSWAVHLES
LEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEAIRQQVEAV
LAGHEAVRWHSEQRLLRRAKRSVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRG
VTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVP
NNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGP
HQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRM
PFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALML
QVRPCLTWRDVQHIIVFTATRYEDRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWT
SVPYLASYVSPVLKENKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRG
SLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDESF
QVGILRQWQLTLYGSVWSAVDIRDRQRLLESAMSGKYLHDDFALPCPPGLKIPEEDGYTI
TPNTLKTLVLVGCFTVFWTVYYMLEVYLSQRNVASNQVCRSGPCHWPHRSRKAKEEGTEL
ESVPLCSSKDPDEVETESRGPPTTSDLLAPDLLEQGDWSLSQNKSALDCPHQHLDVPHGK
EEQIC
|
|
|
|---|
| BDBM50343352 |
|---|
| n/a |
|---|
| Name | BDBM50343352 |
|---|
| Synonyms: | 2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one | 4-(4-hydroxy-2-oxo-2H-3-chromenyl)-4-phenyl-2-butanone | 4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-chromen-2-one | 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one | CHEMBL1464 | Coumadin | Jantoven | Warfarin4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-chromen-2-one | wafarin | warfarin | warfarine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H16O4 |
|---|
| Mol. Mass. | 308.3279 |
|---|
| SMILES | CC(=O)CC(c1ccccc1)c1c(O)c2ccccc2oc1=O |
|---|
| Structure | 
|
|---|
Search and Browse
