| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
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| Ligand | BDBM50350870 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_763496 (CHEMBL1819845) |
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| EC50 | 0.55±n/a nM |
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| Citation |  Wisniewski, K; Galyean, R; Tariga, H; Alagarsamy, S; Croston, G; Heitzmann, J; Kohan, A; Wisniewska, H; Laporte, R; Rivière, PJ; Schteingart, CD New, potent, selective, and short-acting peptidic V1a receptor agonists. J Med Chem54:4388-98 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1a receptor |
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| Name: | Vasopressin V1a receptor |
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| Synonyms: | Avpr1a | V1AR_RAT | VASOPRESSIN V1A | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47674.81 |
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| Organism: | RAT |
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| Description: | VASOPRESSIN V1A AVPR1A RAT::P30560 |
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| Residue: | 424 |
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| Sequence: | MSFPRGSQDRSVGNSSPWWPLTTEGSNGSQEAARLGEGDSPLGDVRNEELAKLEIAVLAV
IFVVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQLCWDITYRFRGP
DWLCRVVKHLQVFAMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIATSWVLSFI
LSTPQYFIFSVIEIEVNNGTKTQDCWATFIQPWGTRAYVTWMTSGVFVAPVVVLGTCYGF
ICYHIWRNIRGKTASSRHSKGDKGSGEAVGPFHKGLLVTPCVSSVKSISRAKIRTVKMTF
VIVSAYILCWAPFFIVQMWSVWDENFIWTDSENPSITITALLASLNSCCNPWIYMFFSGH
LLQDCVQSFPCCHSMAQKFAKDDSDSMSRRQTSYSNNRSPTNSTGMWKDSPKSSKSIRFI
PVST
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| BDBM50350870 |
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| n/a |
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| Name | BDBM50350870 |
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| Synonyms: | CHEMBL1817709 |
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| Type | Small organic molecule |
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| Emp. Form. | C46H73N13O11S2 |
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| Mol. Mass. | 1048.282 |
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| SMILES | CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(C)C)C(=O)NCC(N)=O |r| |
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| Structure | 
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