| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 2 |
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| Ligand | BDBM50352103 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_766639 (CHEMBL1827205) |
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| IC50 | 1100±n/a nM |
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| Citation |  Urbano, M; Guerrero, M; Zhao, J; Velaparthi, S; Schaeffer, MT; Brown, S; Rosen, H; Roberts, E SAR analysis of innovative selective small molecule antagonists of sphingosine-1-phosphate 4 (S1P4) receptor. Bioorg Med Chem Lett21:5470-4 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 2 |
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| Name: | Sphingosine 1-phosphate receptor 2 |
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| Synonyms: | EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 38883.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay. |
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| Residue: | 353 |
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| Sequence: | MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
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| BDBM50352103 |
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| n/a |
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| Name | BDBM50352103 |
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| Synonyms: | CHEMBL1824254 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21NOS |
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| Mol. Mass. | 335.463 |
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| SMILES | Cc1ccc(C)c(c1)-c1ccc(s1)C(=O)Nc1c(C)cccc1C |
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| Structure | 
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