| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Luciferin 4-monooxygenase |
|---|
| Ligand | BDBM50352638 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_766351 (CHEMBL1826377) |
|---|
| IC50 | 6400±n/a nM |
|---|
| Citation |  Xiao, J; Marugan, JJ; Zheng, W; Titus, S; Southall, N; Cherry, JJ; Evans, M; Androphy, EJ; Austin, CP Discovery, synthesis, and biological evaluation of novel SMN protein modulators. J Med Chem54:6215-33 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Luciferin 4-monooxygenase |
|---|
| Name: | Luciferin 4-monooxygenase |
|---|
| Synonyms: | LUCI_AQULA | Luciferase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60126.66 |
|---|
| Organism: | Luciola lateralis |
|---|
| Description: | ChEMBL_786225 |
|---|
| Residue: | 548 |
|---|
| Sequence: | MENMENDENIVYGPEPFYPIEEGSAGAQLRKYMDRYAKLGAIAFTNALTGVDYTYAEYLE
KSCCLGEALKNYGLVVDGRIALCSENCEEFFIPVLAGLFIGVGVAPTNEIYTLRELVHSL
GISKPTIVFSSKKGLDKVITVQKTVTAIKTIVILDSKVDYRGYQSMDNFIKKNTPQGFKG
SSFKTVEVNRKEQVALIMNSSGSTGLPKGVQLTHENAVTRFSHARDPIYGNQVSPGTAIL
TVVPFHHGFGMFTTLGYLTCGFRIVMLTKFDEETFLKTLQDYKCSSVILVPTLFAILNRS
ELLDKYDLSNLVEIASGGAPLSKEIGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDK
PGASGKVVPLFKAKVIDLDTKKTLGPNRRGEVCVKGPMLMKGYVDNPEATREIIDEEGWL
HTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPIAG
ELPGAVVVLEKGKSMTEKEVMDYVASQVSNAKRLRGGVRFVDEVPKGLTGKIDGKAIREI
LKKPVAKM
|
|
|
|---|
| BDBM50352638 |
|---|
| n/a |
|---|
| Name | BDBM50352638 |
|---|
| Synonyms: | CHEMBL1726915 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H19N3OS |
|---|
| Mol. Mass. | 301.407 |
|---|
| SMILES | Cc1ccc(cc1)-c1cnc(s1)N1CCC(CC1)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
