| Reaction Details |
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 | Report a problem with these data |
| Target | Small conductance calcium-activated potassium channel protein 2 |
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| Ligand | BDBM50356159 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_776011 (CHEMBL1913009) |
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| Ki | 194±n/a nM |
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| Citation |  Badarau, E; Dilly, S; Dufour, F; Poncin, S; Seutin, V; Liégeois, JF Synthesis and radioligand binding studies of bis-(8-isopropyl-isoquinolinium) derivatives as ligands for apamin-sensitive sites on cloned SK2 and SK3 channels. Bioorg Med Chem Lett21:6756-9 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Small conductance calcium-activated potassium channel protein 2 |
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| Name: | Small conductance calcium-activated potassium channel protein 2 |
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| Synonyms: | KCNN2 | KCNN2_HUMAN | SK2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63788.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_480083 |
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| Residue: | 579 |
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| Sequence: | MSSCRYNGGVMRPLSNLSASRRNLHEMDSEAQPLQPPASVGGGGGASSPSAAAAAAAAVS
SSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSGTKSSKKKNQNIGYK
LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTII
LLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTAR
LAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF
VMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIG
YGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVK
NAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLV
DLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFI
EAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS
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| BDBM50356159 |
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| n/a |
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| Name | BDBM50356159 |
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| Synonyms: | CHEMBL1909929 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H38N2 |
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| Mol. Mass. | 426.635 |
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| SMILES | CC(C)c1cccc2cc[n+](C)c(CCCCc3[n+](C)ccc4cccc(C(C)C)c34)c12 |
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| Structure | 
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