Compile Data Set for Download or QSAR

Found 234 hits with Last Name = 'badarau' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50307501 ((6S)-N,N-dipropyl-5,6,7,8-tetrahydro-1,1'-binaphth...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1cccc2ccccc12 |r| Show InChI InChI=1S/C26H31N/c1-3-17-27(18-4-2)22-15-16-24-21(19-22)11-8-14-26(24)25-13-7-10-20-9-5-6-12-23(20)25/h5-14,22H,3-4,15-19H2,1-2H3/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139351 (2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...) Show SMILES CN(C)CCSc1cccc(n1)C1CCCCC1 Show InChI InChI=1S/C15H24N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h6,9-10,13H,3-5,7-8,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50150684 ((R)-8-(2,6-dimethoxyphenyl)-N,N-dimethylchroman-3-...) Show SMILES COc1cccc(OC)c1-c1cccc2C[C@H](COc12)N(C)C |wD:16.22,(-5.36,2.24,;-4,1.49,;-2.67,2.28,;-2.7,3.82,;-1.37,4.59,;,3.84,;,2.29,;1.31,1.53,;2.64,2.29,;-1.34,1.53,;-1.34,-.01,;-2.67,-.78,;-2.67,-2.32,;-1.34,-3.09,;,-2.34,;1.31,-3.13,;2.67,-2.34,;2.67,-.78,;1.31,-.01,;,-.78,;4,-3.13,;4,-4.66,;5.35,-2.34,)| Show InChI InChI=1S/C19H23NO3/c1-20(2)14-11-13-7-5-8-15(19(13)23-12-14)18-16(21-3)9-6-10-17(18)22-4/h5-10,14H,11-12H2,1-4H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50150685 (((S)-5-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-...) Show SMILES CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1ccccc1 Show InChI InChI=1S/C22H29N/c1-3-15-23(16-4-2)20-13-14-22-19(17-20)11-8-12-21(22)18-9-6-5-7-10-18/h5-12,20H,3-4,13-17H2,1-2H3/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50150676 (((R)-8-Phenyl-chroman-3-yl)-dipropyl-amine | (R)-8...) Show SMILES CCCN(CCC)[C@H]1COc2c(C1)cccc2-c1ccccc1 Show InChI InChI=1S/C21H27NO/c1-3-13-22(14-4-2)19-15-18-11-8-12-20(21(18)23-16-19)17-9-6-5-7-10-17/h5-12,19H,3-4,13-16H2,1-2H3/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29546 (benzimidazolone scaffold, 15d) Show SMILES COc1ccccc1N1CCN(CCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C21H26N4O2/c1-27-20-10-5-4-9-19(20)24-15-13-23(14-16-24)11-6-12-25-18-8-3-2-7-17(18)22-21(25)26/h2-5,7-10H,6,11-16H2,1H3,(H,22,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3.40	-50.3	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29548 (benzimidazolone scaffold, 15f) Show SMILES COc1ccccc1N1CCN(CCCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C22H28N4O2/c1-28-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-19-9-3-2-8-18(19)23-22(26)27/h2-5,8-11H,6-7,12-17H2,1H3,(H,23,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	6	-48.8	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29549 (benzimidazolone scaffold, 15g) Show SMILES O=c1[nH]c2ccccc2n1CCCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C22H28N4O/c27-22-23-20-11-5-6-12-21(20)26(22)14-8-2-7-13-24-15-17-25(18-16-24)19-9-3-1-4-10-19/h1,3-6,9-12H,2,7-8,13-18H2,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139355 (2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...) Show SMILES CN(C)CCSc1cccc(n1)-c1ccccc1 Show InChI InChI=1S/C15H18N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h3-10H,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29554 (benzimidazolone scaffold, 15m) Show SMILES Clc1ccc(cc1)N1CCN(CCCCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C22H27ClN4O/c23-18-8-10-19(11-9-18)26-16-14-25(15-17-26)12-4-1-5-13-27-21-7-3-2-6-20(21)24-22(27)28/h2-3,6-11H,1,4-5,12-17H2,(H,24,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50210123 (CHEMBL395870 | N,N-dimethyl-2-(2'-methylbiphenyl-3...) Show SMILES CN(C)CCc1cccc(c1)-c1ccccc1C Show InChI InChI=1S/C17H21N/c1-14-7-4-5-10-17(14)16-9-6-8-15(13-16)11-12-18(2)3/h4-10,13H,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29553 (benzimidazolone scaffold, 15k) Show SMILES Clc1cccc(c1)N1CCN(CCCCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C22H27ClN4O/c23-18-7-6-8-19(17-18)26-15-13-25(14-16-26)11-4-1-5-12-27-21-10-3-2-9-20(21)24-22(27)28/h2-3,6-10,17H,1,4-5,11-16H2,(H,24,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139357 (CHEMBL345803 | Dimethyl-[2-(4-phenyl-thiazol-2-yls...) Show SMILES CN(C)CCSc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C13H16N2S2/c1-15(2)8-9-16-13-14-12(10-17-13)11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29552 (benzimidazolone scaffold, 15j) Show SMILES COc1ccccc1N1CCN(CCCCCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C24H32N4O2/c1-30-23-13-7-6-12-22(23)27-18-16-26(17-19-27)14-8-2-3-9-15-28-21-11-5-4-10-20(21)25-24(28)29/h4-7,10-13H,2-3,8-9,14-19H2,1H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	12	-47.0	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50160366 ((S)-6-(2,6-dimethylphenyl)-N,N-dimethylchroman-3-a...) Show SMILES CN(C)[C@@H]1COc2ccc(cc2C1)-c1c(C)cccc1C Show InChI InChI=1S/C19H23NO/c1-13-6-5-7-14(2)19(13)15-8-9-18-16(10-15)11-17(12-21-18)20(3)4/h5-10,17H,11-12H2,1-4H3/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29551 (benzimidazolone scaffold, 15i) Show SMILES O=c1[nH]c2ccccc2n1CCCCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C23H30N4O/c28-23-24-21-12-6-7-13-22(21)27(23)15-9-2-1-8-14-25-16-18-26(19-17-25)20-10-4-3-5-11-20/h3-7,10-13H,1-2,8-9,14-19H2,(H,24,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29540 (benzimidazolone scaffold, 8h) Show SMILES COc1ccc(cc1)-n1c2ccccc2n(CCN2CCN(CC2)c2ccccc2OC)c1=O Show InChI InChI=1S/C27H30N4O3/c1-33-22-13-11-21(12-14-22)31-24-8-4-3-7-23(24)30(27(31)32)20-17-28-15-18-29(19-16-28)25-9-5-6-10-26(25)34-2/h3-14H,15-20H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	22	-45.5	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29544 (benzimidazolone scaffold, 15b) Show SMILES COc1ccccc1N1CCN(CCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C20H24N4O2/c1-26-19-9-5-4-8-18(19)23-13-10-22(11-14-23)12-15-24-17-7-3-2-6-16(17)21-20(24)25/h2-9H,10-15H2,1H3,(H,21,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	25	-45.1	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29548 (benzimidazolone scaffold, 15f) Show SMILES COc1ccccc1N1CCN(CCCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C22H28N4O2/c1-28-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-19-9-3-2-8-18(19)23-22(26)27/h2-5,8-11H,6-7,12-17H2,1H3,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29545 (benzimidazolone scaffold, 15c) Show SMILES O=c1[nH]c2ccccc2n1CCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C20H24N4O/c25-20-21-18-9-4-5-10-19(18)24(20)12-6-11-22-13-15-23(16-14-22)17-7-2-1-3-8-17/h1-5,7-10H,6,11-16H2,(H,21,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	26	-45.0	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29541 (benzimidazolone scaffold, 17d) Show SMILES COc1ccc(cc1)-n1c2ccccc2n(CCCN2CCN(CC2)c2ccccc2OC)c1=O Show InChI InChI=1S/C28H32N4O3/c1-34-23-14-12-22(13-15-23)32-25-9-4-3-8-24(25)31(28(32)33)17-7-16-29-18-20-30(21-19-29)26-10-5-6-11-27(26)35-2/h3-6,8-15H,7,16-21H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	26	-45.0	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50307490 (2-(6-(Furan-3-yl)pyridin-2-yloxy)-N,N-dimethyl-eth...) Show SMILES CN(C)CCSc1cccc(n1)-c1ccoc1 Show InChI InChI=1S/C13H16N2OS/c1-15(2)7-9-17-13-5-3-4-12(14-13)11-6-8-16-10-11/h3-6,8,10H,7,9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50307490 (2-(6-(Furan-3-yl)pyridin-2-yloxy)-N,N-dimethyl-eth...) Show SMILES CN(C)CCSc1cccc(n1)-c1ccoc1 Show InChI InChI=1S/C13H16N2OS/c1-15(2)7-9-17-13-5-3-4-12(14-13)11-6-8-16-10-11/h3-6,8,10H,7,9H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29550 (benzimidazolone scaffold, 15h) Show SMILES COc1ccccc1N1CCN(CCCCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C23H30N4O2/c1-29-22-12-6-5-11-21(22)26-17-15-25(16-18-26)13-7-2-8-14-27-20-10-4-3-9-19(20)24-23(27)28/h3-6,9-12H,2,7-8,13-18H2,1H3,(H,24,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	33	-44.4	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29542 (benzimidazolone scaffold, 17f) Show SMILES COc1ccc(cc1)-n1c2ccccc2n(CCCCN2CCN(CC2)c2ccccc2OC)c1=O Show InChI InChI=1S/C29H34N4O3/c1-35-24-15-13-23(14-16-24)33-26-10-4-3-9-25(26)32(29(33)34)18-8-7-17-30-19-21-31(22-20-30)27-11-5-6-12-28(27)36-2/h3-6,9-16H,7-8,17-22H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	36	-44.2	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139361 (2-(6-Bromopyridin-2-ylthio)-N,N-dimethylethanamine...) Show SMILES CN(C)CCSc1cccc(Br)n1 Show InChI InChI=1S/C9H13BrN2S/c1-12(2)6-7-13-9-5-3-4-8(10)11-9/h3-5H,6-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29550 (benzimidazolone scaffold, 15h) Show SMILES COc1ccccc1N1CCN(CCCCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C23H30N4O2/c1-29-22-12-6-5-11-21(22)26-17-15-25(16-18-26)13-7-2-8-14-27-20-10-4-3-9-19(20)24-23(27)28/h3-6,9-12H,2,7-8,13-18H2,1H3,(H,24,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29546 (benzimidazolone scaffold, 15d) Show SMILES COc1ccccc1N1CCN(CCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C21H26N4O2/c1-27-20-10-5-4-9-19(20)24-15-13-23(14-16-24)11-6-12-25-18-8-3-2-7-17(18)22-21(25)26/h2-5,7-10H,6,11-16H2,1H3,(H,22,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50139355 (2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...) Show SMILES CN(C)CCSc1cccc(n1)-c1ccccc1 Show InChI InChI=1S/C15H18N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h3-10H,11-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 3 (Homo sapiens (Human))	BDBM50356161 (CHEMBL1909931) Show SMILES CC(C)c1cccc2cc[n+](C)c(Cc3cccc(Cc4[n+](C)ccc5cccc(C(C)C)c45)c3)c12 Show InChI InChI=1S/C34H38N2/c1-23(2)29-14-8-12-27-16-18-35(5)31(33(27)29)21-25-10-7-11-26(20-25)22-32-34-28(17-19-36(32)6)13-9-15-30(34)24(3)4/h7-20,23-24H,21-22H2,1-6H3/q+2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [125I]-apamin from cloned SK3 channel expressed in human HEK293 cells after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 6756-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.043 BindingDB Entry DOI: 10.7270/Q2R211S7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29551 (benzimidazolone scaffold, 15i) Show SMILES O=c1[nH]c2ccccc2n1CCCCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C23H30N4O/c28-23-24-21-12-6-7-13-22(21)27(23)15-9-2-1-8-14-25-16-18-26(19-17-25)20-10-4-3-5-11-20/h3-7,10-13H,1-2,8-9,14-19H2,(H,24,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	48	-43.5	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29547 (benzimidazolone scaffold, 15e) Show SMILES O=c1[nH]c2ccccc2n1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C21H26N4O/c26-21-22-19-10-4-5-11-20(19)25(21)13-7-6-12-23-14-16-24(17-15-23)18-8-2-1-3-9-18/h1-5,8-11H,6-7,12-17H2,(H,22,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29553 (benzimidazolone scaffold, 15k) Show SMILES Clc1cccc(c1)N1CCN(CCCCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C22H27ClN4O/c23-18-7-6-8-19(17-18)26-15-13-25(14-16-26)11-4-1-5-12-27-21-10-3-2-9-20(21)24-22(27)28/h2-3,6-10,17H,1,4-5,11-16H2,(H,24,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	66	-42.6	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29552 (benzimidazolone scaffold, 15j) Show SMILES COc1ccccc1N1CCN(CCCCCCn2c3ccccc3[nH]c2=O)CC1 Show InChI InChI=1S/C24H32N4O2/c1-30-23-13-7-6-12-22(23)27-18-16-26(17-19-27)14-8-2-3-9-15-28-21-11-5-4-10-20(21)25-24(28)29/h4-7,10-13H,2-3,8-9,14-19H2,1H3,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29547 (benzimidazolone scaffold, 15e) Show SMILES O=c1[nH]c2ccccc2n1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C21H26N4O/c26-21-22-19-10-4-5-11-20(19)25(21)13-7-6-12-23-14-16-24(17-15-23)18-8-2-1-3-9-18/h1-5,8-11H,6-7,12-17H2,(H,22,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	84	-42.0	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Homo sapiens (Human))	BDBM50356161 (CHEMBL1909931) Show SMILES CC(C)c1cccc2cc[n+](C)c(Cc3cccc(Cc4[n+](C)ccc5cccc(C(C)C)c45)c3)c12 Show InChI InChI=1S/C34H38N2/c1-23(2)29-14-8-12-27-16-18-35(5)31(33(27)29)21-25-10-7-11-26(20-25)22-32-34-28(17-19-36(32)6)13-9-15-30(34)24(3)4/h7-20,23-24H,21-22H2,1-6H3/q+2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [125I]-apamin from cloned SK2 channel expressed in human HEK293 cells after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 6756-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.043 BindingDB Entry DOI: 10.7270/Q2R211S7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50307488 (2-(6-(2,6-Dimethylphenyl)pyridin-2-ylthio)-N,Ndime...) Show SMILES CN(C)CCSc1cccc(n1)-c1c(C)cccc1C Show InChI InChI=1S/C17H22N2S/c1-13-7-5-8-14(2)17(13)15-9-6-10-16(18-15)20-12-11-19(3)4/h5-10H,11-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50139361 (2-(6-Bromopyridin-2-ylthio)-N,N-dimethylethanamine...) Show SMILES CN(C)CCSc1cccc(Br)n1 Show InChI InChI=1S/C9H13BrN2S/c1-12(2)6-7-13-9-5-3-4-8(10)11-9/h3-5H,6-7H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampus				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50307494 (2-(Biphenyl-2-yloxy)-N,N-dimethylethanamine | CHEM...) Show SMILES CN(C)CCOc1ccccc1-c1ccccc1 Show InChI InChI=1S/C16H19NO/c1-17(2)12-13-18-16-11-7-6-10-15(16)14-8-4-3-5-9-14/h3-11H,12-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells				Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM233049 (2-[2-(6-Chloropyrrolo[2,3-b]pyridin-1-yl)ethyl]dec...) Show SMILES Clc1ccc2ccn(CCN3CCCN4CCCCC4C3)c2n1 Show InChI InChI=1S/C18H25ClN4/c19-17-6-5-15-7-11-23(18(15)20-17)13-12-21-8-3-10-22-9-2-1-4-16(22)14-21/h5-7,11,16H,1-4,8-10,12-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Orléans					Assay Description 1H nuclear magnetic resonance (NMR) and 13C NMR spectra were recorded on a Bruker Avance DPX250 spectrometer (250.131 MHz), in CDCl3 and using tetram...				J Enzyme Inhib Med Chem 25: 301-5 (2010) Article DOI: 10.3109/14756360903179393 BindingDB Entry DOI: 10.7270/Q2B85708
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29541 (benzimidazolone scaffold, 17d) Show SMILES COc1ccc(cc1)-n1c2ccccc2n(CCCN2CCN(CC2)c2ccccc2OC)c1=O Show InChI InChI=1S/C28H32N4O3/c1-34-23-14-12-22(13-15-23)32-25-9-4-3-8-24(25)31(28(32)33)17-7-16-29-18-20-30(21-19-29)26-10-5-6-11-27(26)35-2/h3-6,8-15H,7,16-21H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	168	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29537 (benzimidazolone scaffold, 8e) Show SMILES Cc1ccccc1N1CCN(CCn2c3ccccc3n(-c3ccccc3)c2=O)CC1 Show InChI InChI=1S/C26H28N4O/c1-21-9-5-6-12-23(21)28-18-15-27(16-19-28)17-20-29-24-13-7-8-14-25(24)30(26(29)31)22-10-3-2-4-11-22/h2-14H,15-20H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	168	-40.2	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29539 (benzimidazolone scaffold, 8g) Show SMILES COc1cccc(c1)-n1c2ccccc2n(CCN2CCN(CC2)c2ccccc2C)c1=O Show InChI InChI=1S/C27H30N4O2/c1-21-8-3-4-11-24(21)29-17-14-28(15-18-29)16-19-30-25-12-5-6-13-26(25)31(27(30)32)22-9-7-10-23(20-22)33-2/h3-13,20H,14-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	182	-40.0	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 2 (Homo sapiens (Human))	BDBM50356159 (CHEMBL1909929) Show SMILES CC(C)c1cccc2cc[n+](C)c(CCCCc3[n+](C)ccc4cccc(C(C)C)c34)c12 Show InChI InChI=1S/C30H38N2/c1-21(2)25-13-9-11-23-17-19-31(5)27(29(23)25)15-7-8-16-28-30-24(18-20-32(28)6)12-10-14-26(30)22(3)4/h9-14,17-22H,7-8,15-16H2,1-6H3/q+2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	194	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [125I]-apamin from cloned SK2 channel expressed in human HEK293 cells after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 6756-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.043 BindingDB Entry DOI: 10.7270/Q2R211S7
					More data for this Ligand-Target Pair
Small conductance calcium-activated potassium channel protein 3 (Homo sapiens (Human))	BDBM50356159 (CHEMBL1909929) Show SMILES CC(C)c1cccc2cc[n+](C)c(CCCCc3[n+](C)ccc4cccc(C(C)C)c34)c12 Show InChI InChI=1S/C30H38N2/c1-21(2)25-13-9-11-23-17-19-31(5)27(29(23)25)15-7-8-16-28-30-24(18-20-32(28)6)12-10-14-26(30)22(3)4/h9-14,17-22H,7-8,15-16H2,1-6H3/q+2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	214	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Li£ge Curated by ChEMBL					Assay Description Displacement of [125I]-apamin from cloned SK3 channel expressed in human HEK293 cells after 1 hr by liquid scintillation counting				Bioorg Med Chem Lett 21: 6756-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.043 BindingDB Entry DOI: 10.7270/Q2R211S7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29545 (benzimidazolone scaffold, 15c) Show SMILES O=c1[nH]c2ccccc2n1CCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C20H24N4O/c25-20-21-18-9-4-5-10-19(18)24(20)12-6-11-22-13-15-23(16-14-22)17-7-2-1-3-8-17/h1-5,7-10H,6,11-16H2,(H,21,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	243	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29542 (benzimidazolone scaffold, 17f) Show SMILES COc1ccc(cc1)-n1c2ccccc2n(CCCCN2CCN(CC2)c2ccccc2OC)c1=O Show InChI InChI=1S/C29H34N4O3/c1-35-24-15-13-23(14-16-24)33-26-10-4-3-9-25(26)32(29(33)34)18-8-7-17-30-19-21-31(22-20-30)27-11-5-6-12-28(27)36-2/h3-6,9-16H,7-8,17-22H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	267	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29549 (benzimidazolone scaffold, 15g) Show SMILES O=c1[nH]c2ccccc2n1CCCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C22H28N4O/c27-22-23-20-11-5-6-12-21(20)26(22)14-8-2-7-13-24-15-17-25(18-16-24)19-9-3-1-4-10-19/h1,3-6,9-12H,2,7-8,13-18H2,(H,23,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	269	-39.0	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM29540 (benzimidazolone scaffold, 8h) Show SMILES COc1ccc(cc1)-n1c2ccccc2n(CCN2CCN(CC2)c2ccccc2OC)c1=O Show InChI InChI=1S/C27H30N4O3/c1-33-22-13-11-21(12-14-22)31-24-8-4-3-7-23(24)30(27(31)32)20-17-28-15-18-29(19-16-28)25-9-5-6-10-26(25)34-2/h3-14H,15-20H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	296	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM29536 (benzimidazolone scaffold, 8d) Show SMILES COc1ccc(cc1)-n1c2ccccc2n(CCN2CCN(CC2)c2ccccc2)c1=O Show InChI InChI=1S/C26H28N4O2/c1-32-23-13-11-22(12-14-23)30-25-10-6-5-9-24(25)29(26(30)31)20-17-27-15-18-28(19-16-27)21-7-3-2-4-8-21/h2-14H,15-20H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	340	-38.4	n/a	n/a	n/a	n/a	n/a	7.4	37
CNRS					Assay Description Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...				Bioorg Med Chem Lett 19: 1600-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.008 BindingDB Entry DOI: 10.7270/Q2KS6PW1
					More data for this Ligand-Target Pair

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