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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Platelet-derived growth factor receptor beta | ||
| Ligand | BDBM50357884 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_786776 (CHEMBL1919617) | ||
| IC50 | >10000±n/a nM | ||
| Citation |  Lumeras, W; Vidal, L; Vidal, B; Balagué, C; Orellana, A; Maldonado, M; Domínguez, M; Segarra, V; Caturla, F 1,7-Naphthyridine 1-oxides as novel potent and selective inhibitors of p38 mitogen activated protein kinase. J Med Chem54:7899-910 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Platelet-derived growth factor receptor beta | |||
| Name: | Platelet-derived growth factor receptor beta | ||
| Synonyms: | Beta-type platelet-derived growth factor receptor | CD140 antigen-like family member B | CD140b antigen | CD_antigen=CD140b | PDGF Receptor Substrate | PDGF-R-beta | PDGFR | PDGFR substrate | PDGFR-1 | PDGFR1 | PDGFRB | PDGFRbeta | PGFRB_HUMAN | Platelet-Derived Growth Factor Receptor, beta | Platelet-derived growth factor receptor 1 | Platelet-derived growth factor receptor beta | Platelet-derived growth factor receptor beta (PDGFR-beta) | Platelet-derived growth factor receptor beta (PDGFRB) | Platelet-derived growth factor receptor beta (PDGFRbeta) | VHL/PDGFRB | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 123922.25 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P09619 | ||
| Residue: | 1106 | ||
| Sequence: |
| ||
| BDBM50357884 | |||
| n/a | |||
| Name | BDBM50357884 | ||
| Synonyms: | CHEMBL1916359 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H10Cl3FN2O | ||
| Mol. Mass. | 419.664 | ||
| SMILES | [O-][n+]1ccc2c(ccnc2c1-c1c(Cl)cccc1Cl)-c1ccc(F)cc1Cl |(12.75,-22.82,;14.08,-22.05,;14.08,-20.51,;15.41,-19.74,;16.75,-20.5,;18.08,-19.73,;19.42,-20.51,;19.42,-22.05,;18.08,-22.82,;16.74,-22.05,;15.42,-22.83,;15.42,-24.36,;14.08,-25.13,;12.75,-24.36,;14.09,-26.67,;15.42,-27.44,;16.76,-26.66,;16.75,-25.12,;18.08,-24.34,;18.08,-18.2,;19.42,-17.43,;19.42,-15.89,;18.08,-15.12,;18.08,-13.58,;16.75,-15.89,;16.75,-17.43,;15.42,-18.2,)| | ||
| Structure | 
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