| Reaction Details |
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 | Report a problem with these data |
| Target | Enoyl-acyl-carrier protein reductase |
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| Ligand | BDBM8726 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_795989 (CHEMBL1936261) |
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| IC50 | 70±n/a nM |
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| Citation |  Muhammad, A; Anis, I; Ali, Z; Awadelkarim, S; Khan, A; Khalid, A; Shah, MR; Galal, M; Khan, IA; Iqbal Choudhary, M Methylenebissantin: a rare methylene-bridged bisflavonoid from Dodonaea viscosa which inhibits Plasmodium falciparum enoyl-ACP reductase. Bioorg Med Chem Lett22:610-2 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Enoyl-acyl-carrier protein reductase |
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| Name: | Enoyl-acyl-carrier protein reductase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49770.86 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_795989 |
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| Residue: | 432 |
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| Sequence: | MNKISQRLLFLFLHFYTTVCFIQNNTQKTFHNVLQNEQIRGKEKAFYRKEKRENIFIGNK
MKHVHNMNNTHNNNHYMEKEEQDASNINKIKEENKNEDICFIAGIGDTNGYGWGIAKELS
KRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEE
TKNNKRYNMLQNYPIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSK
SSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLG
RNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSHDVHNIMNNSGEKEEKKN
SASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIM
FLPDDIYRNENE
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| BDBM8726 |
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| n/a |
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| Name | BDBM8726 |
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| Synonyms: | 5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849 | TCL | Triclosan | US20230414581, Compound 35 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H7Cl3O2 |
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| Mol. Mass. | 289.542 |
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| SMILES | Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl |
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| Structure | 
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