| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 4 |
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| Ligand | BDBM75598 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_795350 (CHEMBL1937206) |
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| EC50 | 7200±n/a nM |
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| Citation |  Guerrero, M; Urbano, M; Zhao, J; Crisp, M; Chase, P; Hodder, P; Schaeffer, MT; Brown, S; Rosen, H; Roberts, E Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonists. Bioorg Med Chem Lett22:537-42 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 4 |
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| Name: | Sphingosine 1-phosphate receptor 4 |
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| Synonyms: | EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41647.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 384 |
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| Sequence: | MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
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| BDBM75598 |
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| n/a |
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| Name | BDBM75598 |
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| Synonyms: | 3-[2-(2,4-dimethylphenoxy)ethoxy]-6-methyl-2-nitro-pyridine | 3-[2-(2,4-dimethylphenoxy)ethoxy]-6-methyl-2-nitropyridine | CYM5954 | SR-02000000300 | SR-02000000300-1 | cid_44620886 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H18N2O4 |
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| Mol. Mass. | 302.3251 |
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| SMILES | Cc1ccc(OCCOc2ccc(C)nc2[N+]([O-])=O)c(C)c1 |
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| Structure | 
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